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Literature DB >> 21779596

Recent advances in indole syntheses: new routes for a classic target.

Abstract

Indoles are the most abundant heterocycles in biologically active natural products, pharmaceuticals, agrochemicals, and are relevant substructures in functional materials. As a result, the development of methodologies that enable the synthesis of these compounds is continuously demanded. This review summarizes most recent and relevant approaches towards the preparation of this prevalent structural motif.

Entities: Chemical

Mesh：

Substances：
Indoles
indole

Year: 2011 PMID： 21779596 DOI： 10.1039/c1ob05750b

Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876

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Cited

22 in total

1. Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations.

Authors: Xiaoxun Li; Hui Li; Wangze Song; Po-Sen Tseng; Lingyan Liu; Ilia A Guzei; Weiping Tang
Journal: Angew Chem Int Ed Engl Date: 2015-09-07 Impact factor: 15.336

2. Friedel-Crafts Alkylation of Indoles with Trichloroacetimidates.

Authors: Tamie Suzuki; John D Chisholm
Journal: Tetrahedron Lett Date: 2019-04-03 Impact factor: 2.415

3. Platinum-catalyzed tandem indole annulation/arylation for the synthesis of diindolylmethanes and indolo[3,2-b]carbazoles.

Authors: Dongxu Shu; Gabrielle N Winston-McPherson; Wangze Song; Weiping Tang
Journal: Org Lett Date: 2013-08-05 Impact factor: 6.005

4. Computational study of Ru-catalyzed cycloisomerization of 2-alkynylanilides.

Authors: Xinghui Zhang; Shanshan Li; Xiaoli Wei; Yun Lei
Journal: J Mol Model Date: 2018-06-14 Impact factor: 1.810

5. Replacement of Stoichiometric DDQ with a Low Potential o-Quinone Catalyst Enabling Aerobic Dehydrogenation of Tertiary Indolines in Pharmaceutical Intermediates.

Authors: Bao Li; Alison E Wendlandt; Shannon S Stahl
Journal: Org Lett Date: 2019-01-31 Impact factor: 6.005

10. Rhodium- and platinum-catalyzed [4+3] cycloaddition with concomitant indole annulation: synthesis of cyclohepta[b]indoles.

Authors: Dongxu Shu; Wangze Song; Xiaoxun Li; Weiping Tang
Journal: Angew Chem Int Ed Engl Date: 2013-02-10 Impact factor: 15.336

Recent advances in indole syntheses: new routes for a classic target.

1. Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations.

2. Friedel-Crafts Alkylation of Indoles with Trichloroacetimidates.

3. Platinum-catalyzed tandem indole annulation/arylation for the synthesis of diindolylmethanes and indolo[3,2-b]carbazoles.

4. Computational study of Ru-catalyzed cycloisomerization of 2-alkynylanilides.

5. Replacement of Stoichiometric DDQ with a Low Potential o-Quinone Catalyst Enabling Aerobic Dehydrogenation of Tertiary Indolines in Pharmaceutical Intermediates.

6. Theoretical study of the regioselective cyclization of enaminones in the construction of benzofurans and indoles.

7. Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors.

8. Copper-catalyzed tandem annulation/arylation for the synthesis of diindolylmethanes from propargylic alcohols.

9. Rhodium(I)-Catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles.

10. Rhodium- and platinum-catalyzed [4+3] cycloaddition with concomitant indole annulation: synthesis of cyclohepta[b]indoles.