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Literature DB >> 21775208

Tackling transcription factors: challenges in antitumor therapy.

Petros D Grivas, Hippokratis Kiaris, Athanasios G Papavassiliou.

Abstract

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Substances：

Year: 2011 PMID： 21775208 DOI： 10.1016/j.molmed.2011.06.005

Source DB: PubMed Journal: Trends Mol Med ISSN： 1471-4914 Impact factor: 11.951

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7 in total

1. A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine.

Authors: Nicholas G Paciaroni; Ranjala Ratnayake; James H Matthews; Verrill M Norwood; Austin C Arnold; Long H Dang; Hendrik Luesch; Robert W Huigens
Journal: Chemistry Date: 2017-02-03 Impact factor: 5.236

2. Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets.

Authors: Nicholas G Paciaroni; Verrill M Norwood; Ranjala Ratnayake; Hendrik Luesch; Robert W Huigens
Journal: Bioorg Med Chem Date: 2020-05-07 Impact factor: 3.641

Review 3. Targeting transcription factor corepressors in tumor cells.

Authors: Aristeidis G Vaiopoulos; Ioannis D Kostakis; Kalliopi Ch Athanasoula; Athanasios G Papavassiliou
Journal: Cell Mol Life Sci Date: 2012-04-19 Impact factor: 9.261

4. A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products.

Authors: Robert W Huigens; Karen C Morrison; Robert W Hicklin; Timothy A Flood; Michelle F Richter; Paul J Hergenrother
Journal: Nat Chem Date: 2013-01-20 Impact factor: 24.427

Tackling transcription factors: challenges in antitumor therapy.

1. A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine.

2. Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets.

Review 3. Targeting transcription factor corepressors in tumor cells.

4. A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products.

5. Limonin as a Starting Point for the Construction of Compounds with High Scaffold Diversity.

6. Genome-wide modulation of gene transcription in ovarian carcinoma cells by a new mithramycin analogue.

7. Diversity-oriented synthetic strategy for developing a chemical modulator of protein-protein interaction.