Literature DB >> 21775010

Sphingosine-1-phosphate induced vasoconstriction is increased in the isolated perfused kidneys of diabetic rats.

Rocio Bautista-Pérez1, Abraham Arellano, Martha Franco, Horacio Osorio, Israel Coronel.   

Abstract

We observed that in isolated perfused rat kidneys, sphingosine-1-phosphate produces S1P(2) receptor-mediated vasoconstriction, and this response increased in kidneys of diabetic rats. These results suggest that the antagonists of S1P(2) receptor may have potential as drugs to control diabetes-induced vascular complications.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2011        PMID： 21775010     DOI： 10.1016/j.diabres.2011.06.023

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN： 0168-8227            Impact factor:   5.602


  6 in total

1.  Mechanisms of sphingosine-1-phosphate-mediated vasoconstriction of rat afferent arterioles.

Authors:  Z Guan; F Wang; X Cui; E W Inscho
Journal:  Acta Physiol (Oxf)       Date:  2017-07-13       Impact factor: 6.311

2.  Sphingosine-1-phosphate evokes unique segment-specific vasoconstriction of the renal microvasculature.

Authors:  Zhengrong Guan; Sean T Singletary; Anthony K Cook; Janet L Hobbs; Jennifer S Pollock; Edward W Inscho
Journal:  J Am Soc Nephrol       Date:  2014-02-27       Impact factor: 10.121

Review 3.  The role of sphingosine-1-phosphate in endothelial barrier function.

Authors:  Brent A Wilkerson; Kelley M Argraves
Journal:  Biochim Biophys Acta       Date:  2014-07-05

4.  Synthesis and characterization of [125I]TZ6544, a promising radioligand for investigating sphingosine-1-phosphate receptor 2.

Authors:  Zonghua Luo; Qianwa Liang; Hui Liu; Joshi Sumit; Hao Jiang; Robyn S Klein; Zhude Tu
Journal:  Nucl Med Biol       Date:  2020-07-27       Impact factor: 2.408

Review 5.  Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks.

Authors:  Kira V Blankenbach; Stephanie Schwalm; Josef Pfeilschifter; Dagmar Meyer Zu Heringdorf
Journal:  Front Pharmacol       Date:  2016-06-21       Impact factor: 5.810

6.  Effect of Empagliflozin on Sphingolipid Catabolism in Diabetic and Hypertensive Rats.

Authors:  Roxana Pérez-Villavicencio; Javier Flores-Estrada; Martha Franco; Bruno Escalante; Oscar Pérez-Méndez; Adriana Mercado; Rocio Bautista-Pérez
Journal:  Int J Mol Sci       Date:  2022-03-07       Impact factor: 5.923
  6 in total

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