Literature DB >> 21773949

High expression of TGF-β1 in the vaginal incisional margin predicts poor prognosis in patients with stage Ib-IIa cervical squamous cell carcinoma.

Dong-Mei Fan1, Xin-Jun Wang, Tao He, Yan Wang, Dan Zhou, Guo-Qiang Kong, Tao Jiang, Mei-Mei Zhang.   

Abstract

This study evaluated the relationship between altered cytoplasmic expression of TGF-β1 in tissues of the vaginal incisional margin and vaginal cancer recurrence in patients with stage Ib-IIa cervical squamous cell carcinoma (CSCC). This paper also discusses the prognostic value of TGF-β1 expression at these locations. We found that TGF-β1 expression in the vaginal margin had a close association with vaginal recurrence of stage Ib-IIa CSCC and was an independent prognostic marker of this disease.

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Year:  2011        PMID： 21773949     DOI： 10.1007/s11033-011-1171-x

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  18 in total

1.  Overexpression of p34cdc2 protein kinase in epithelial ovarian carcinoma.

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Journal:  Mayo Clin Proc       Date:  1997-10       Impact factor: 7.616

2.  Concurrent cisplatin-based chemoradiation for cervical carcinoma: tumor response, toxicity, and serum cytokine profiles.

Authors:  Yuh-Cheng Yang; Kung-Liahng Wang; Tsung-Hsien Su; Hui-Fen Liao; Meng-Hao Wu; Tze-Chien Chen; Ming-Chao Huang; Yu-Jen Chen
Journal:  Cancer Invest       Date:  2006 Jun-Jul       Impact factor: 2.176

3.  MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells.

Authors:  M P Ponnusamy; I Lakshmanan; M Jain; S Das; S Chakraborty; P Dey; S K Batra
Journal:  Oncogene       Date:  2010-08-09       Impact factor: 9.867

4.  Expression of CD34, alpha-smooth muscle actin and transforming growth factor-beta1 in squamous intraepithelial lesions and squamous cell carcinoma of the cervix.

Authors:  Q Li; W Huang; X Zhou
Journal:  J Int Med Res       Date:  2009 Mar-Apr       Impact factor: 1.671

5.  Prognostic significance of histology and positive lymph node involvement following radical hysterectomy in carcinoma of the cervix.

Authors:  O Kenneth Macdonald; Jergin Chen; Mark Dodson; Christopher M Lee; David K Gaffney
Journal:  Am J Clin Oncol       Date:  2009-08       Impact factor: 2.339

6.  [Treatment protocol for cervical carcinoma].

Authors:  Tamara Vujkov; Milica Zivaljević; Petar Novaković; Marko Erak; Jelka Rajović; Aljosa Mandić
Journal:  Med Pregl       Date:  2002 Mar-Apr

7.  Epithelial-mesenchymal transition induced by transforming growth factor-beta1 in mouse tracheal epithelial cells.

Authors:  Shigeki Kuroishi; Takafumi Suda; Tomoyuki Fujisawa; Kyotaro Ide; Naoki Inui; Yutaro Nakamura; Hirotoshi Nakamura; Kingo Chida
Journal:  Respirology       Date:  2009-07-29       Impact factor: 6.424

8.  Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

Authors:  Yujin Hoshida; Augusto Villanueva; Masahiro Kobayashi; Judit Peix; Derek Y Chiang; Amy Camargo; Supriya Gupta; Jamie Moore; Matthew J Wrobel; Jim Lerner; Michael Reich; Jennifer A Chan; Jonathan N Glickman; Kenji Ikeda; Masaji Hashimoto; Goro Watanabe; Maria G Daidone; Sasan Roayaie; Myron Schwartz; Swan Thung; Helga B Salvesen; Stacey Gabriel; Vincenzo Mazzaferro; Jordi Bruix; Scott L Friedman; Hiromitsu Kumada; Josep M Llovet; Todd R Golub
Journal:  N Engl J Med       Date:  2008-10-15       Impact factor: 91.245

9.  Epidemiological characteristics of carcinoma of the cervix in the Federal capital Territory of Nigeria.

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Journal:  Niger J Clin Pract       Date:  2007-06       Impact factor: 0.968

10.  Cyr61, a member of ccn (connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed) family, predicts survival of patients with endometrial cancer of endometrioid subtype.

Authors:  Hidemichi Watari; Ying Xiong; Mohamed K Hassan; Noriaki Sakuragi
Journal:  Gynecol Oncol       Date:  2008-11-12       Impact factor: 5.482
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  3 in total

Review 1.  Transforming growth factor-β1 in carcinogenesis, progression, and therapy in cervical cancer.

Authors:  Haiyan Zhu; Hui Luo; Zhaojun Shen; Xiaoli Hu; Luzhe Sun; Xueqiong Zhu
Journal:  Tumour Biol       Date:  2016-03-24

2.  Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells.

Authors:  Pooja Chandrakant Thacker; Devarajan Karunagaran
Journal:  PLoS One       Date:  2015-03-18       Impact factor: 3.240

Review 3.  Mechanistic basis and clinical relevance of the role of transforming growth factor-β in cancer.

Authors:  Run-Long Lin; Lu-Jun Zhao
Journal:  Cancer Biol Med       Date:  2015-12       Impact factor: 4.248
  3 in total

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