Sir,Filariasis is an important tropical vector-borne infection. This disease can cause chronic infection and suffering to the infected cases. Filariasis is accepted as the most common infectious cause of disability. Of several problems, reproductive disturbance and induction of infertility can be seen. Generally, the well-known situation is the filarial orchitis. However, there are other conditions of filariasis that can lead to infertility. An important rare condition is the existence of filarial worm in follicular fluid. It is extremely rare and has just been documented for a few years. This condition is the accidental finding of filarial worm in the aspirated follicular fluid of infertile females getting in vitro fertilization (IVF) with embryo transfer because of tubal pathology. Surprisingly, it has never been known that the filariasis can cause the problem in female internal sexual organ until the promotion of the advanced IVF technology. In the index cases, the previous infertility and failure of IVF is common.[1-3] The species of identified filarial worms include Wuchereria bancrofti and Mansonella perstans.[1-2] All indexed cases are the migrant infertilewomen from endemic area.[1-2] However, the actual effect of filariasis at this site on reproductive health is not well documented and can be the future topic of research.[3] However, this is an actual new concern in tropical medicine, travel medicine, and reproductive medicine.