| Literature DB >> 21772229 |
Marieke E B Welzen1, Roger J M Brüggemann, J Merlijn Van Den Berg, Heleen W Voogt, Jos H Gilissen, Dasja Pajkrt, Nigel Klein, David M Burger, Adilia Warris.
Abstract
Posaconazole (PSZ) may be an attractive alternative for antifungal prophylaxis in children with chronic granulomatous disease. Experience with PSZ in pediatric patients is limited, and no specific dose recommendations exist. A twice daily dosing algorithm based on allometric scaling (body-weight based) for PSZ results in adequate exposure and appears to be safe in children with chronic granulomatous disease.Entities:
Mesh:
Substances:
Year: 2011 PMID: 21772229 DOI: 10.1097/INF.0b013e3182195808
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN: 0891-3668 Impact factor: 2.129