Literature DB >> 217720

Decreased cyclic GMP levels in rat cecum mucosa during adaptive stimulation of Na-K-ATPase.

R Grezer, K Loeschke.   

Abstract

In rat cecal mucosa, Na-K-ATPase specific activity and sodium and fluid absorption were increased by giving polyethylene glycol administration with the drinking water. Whereas cyclic AMP levels were unchanged, cyclic GMP was reduced by about 50%. This finding suggests a regulatory role of cyclic GMP in intestinal sodium and fluid absorption.

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Year:  1979        PMID： 217720     DOI： 10.1007/bf01920612

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

Review 1.  ION transport by mammalian small intestine.

Authors:  S G Schultz; R A Frizzell; H N Nellans
Journal:  Annu Rev Physiol       Date:  1974       Impact factor: 19.318

2.  Sodium nitroprusside and other smooth muscle-relaxants increase cyclic GMP levels in rat ductus deferens.

Authors:  K Schultz; K Schultz; G Schultz
Journal:  Nature       Date:  1977-02-24       Impact factor: 49.962

3.  Adenylate and guanylate cyclase activities and cellular differentiation in rat small intestine.

Authors:  H Quill; M M Weiser
Journal:  Gastroenterology       Date:  1975-08       Impact factor: 22.682

4.  Ion transport by rabbit colon. I. Active and passive components.

Authors:  R A Frizzell; M J Koch; S G Schultz
Journal:  J Membr Biol       Date:  1976       Impact factor: 1.843

5.  An improved protein binding assay for cyclic AMP.

Authors:  C O Brostrom; C Kon
Journal:  Anal Biochem       Date:  1974-04       Impact factor: 3.365

6.  Ion transport in rabbit ileal mucosa. 3. Effects of catecholamines.

Authors:  M Field; I McColl
Journal:  Am J Physiol       Date:  1973-10

7.  Stimulation of sodium transport and Na+-K+-ATPase activity in the hypertrophying rat cecum.

Authors:  K Loeschke; E Uhlich; R Kinne
Journal:  Pflugers Arch       Date:  1974       Impact factor: 3.657

8.  Induction of Na-K-ATPase in plasma membranes to rat cecum mucosa by diet: time course and kinetics.

Authors:  H Schiffl; K Loeschke
Journal:  Pflugers Arch       Date:  1977-11-25       Impact factor: 3.657

9.  Intestinal mucosal cyclic GMP: regulation and relation to ion transport.

Authors:  T A Brasitus; M Field; D V Kimberg
Journal:  Am J Physiol       Date:  1976-07

10.  Nucleic acid and protein content of rat cecum mucosa in dietary adaptation-growth by cellular hyperplasia.

Authors:  K Loeschke; W Resch
Journal:  Pflugers Arch       Date:  1977-11-25       Impact factor: 3.657
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  6 in total

1.  Adaptation of electrolyte transport in rat large intestine after proximal resection. II. Colon after 50% jejunoilectomy combined with cecectomy.

Authors:  J Fabritius; G Nell; K Loeschke
Journal:  Pflugers Arch       Date:  1986-03       Impact factor: 3.657

2.  Evidence against cyclic GMP acting as a direct modulator of active sodium absorption in rat cecum.

Authors:  P Blümel; R Gerzer; K Loeschke
Journal:  Experientia       Date:  1981-02-15

3.  Discrepancy between effects of cholera toxin on net fluid movement and cAMP levels in rat jejunum, ileum, and colon.

Authors:  U M Farack; R Gerzer; T M Keravis; K Loeschke
Journal:  Dig Dis Sci       Date:  1988-09       Impact factor: 3.199

4.  Inhibition by loperamide of deoxycholic acid induced intestinal secretion.

Authors:  U M Farack; K Loeschke
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-03       Impact factor: 3.000

5.  Effect of diphenolic laxatives on Na+-K+-activated ATPase and cyclic nucleotide content of rat colon mucosa in vivo.

Authors:  J Schreiner; G Nell; K Loeschke
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-09       Impact factor: 3.000

6.  Loperamide reduces the intestinal secretion but not the mucosal cAMP accumulation induced by choleratoxin.

Authors:  U M Farack; U Kautz; K Loeschke
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-09       Impact factor: 3.000
  6 in total

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