| Literature DB >> 2177117 |
Y Kiso1, K Yoshida, K Kaise, N Kaise, T Masuda, N Ando, M Kameyama, M Yamamoto, T Sakurada, K Yoshinaga.
Abstract
A 27-year-old man had symptoms of hyperthyroidism and periodic paralysis. While hyperthyroid, his serum thyrotropin (TSH) level was inappropriately elevated at 6.4 microU/ml. The serum alpha subunit level was also elevated. MR imaging revealed a pituitary tumor and transsphenoidal adenomectomy was performed. Immunocytochemistry with an antibody directed against the beta-subunit of TSH revealed a TSH-secreting tumor. This is the first case of hyperthyroidism due to a TSH-secreting pituitary tumor complicated by periodic paralysis. This association indicates that thyrotoxicosis may induce paralysis in susceptible persons by a mechanism which is not autoimmune.Entities:
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Year: 1990 PMID： 2177117 DOI： 10.2169/internalmedicine1962.29.399
Source DB: PubMed Journal: Jpn J Med ISSN： 0021-5120