| Literature DB >> 21770363 |
Xi Zhu1, Aijun Lin, Yan Shi, Jingyu Guo, Chengjian Zhu, Yixiang Cheng.
Abstract
A facile in situ formed primary amine-imine organocatalyst was developed in the asymmetric Michael addition of substituted 4-hydroxycoumarins to cyclic enones. A series of optically active polycyclic coumarin derivatives were obtained in high yields with excellent enantioselectivities up to 97% ee.Entities:
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Year: 2011 PMID： 21770363 DOI： 10.1021/ol201715h
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005