Literature DB >> 2177019

The dihydropyridine-sensitive calcium channel of the skeletal muscle: biochemistry and structure.

W Nastainczyk1, A Ludwig, F Hofmann.   

Abstract

The dihydropyridine-sensitive calcium channel of the rabbit skeletal muscle is the first voltage-gated calcium channel which has been purified and biochemically characterized. The alpha 1-subunit, a 165 kDa protein, of the purified dihydropyridine receptor contains all regulatory sites of a L-type calcium channel and the calcium conducting unit. The purpose of this review is to summarize and discuss recent findings on the structure and possible function of the skeletal muscle calcium channel subunits.

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Year:  1990        PMID: 2177019

Source DB:  PubMed          Journal:  Gen Physiol Biophys        ISSN: 0231-5882            Impact factor:   1.512


  5 in total

1.  Regional expression and cellular localization of the alpha1 and beta subunit of high voltage-activated calcium channels in rat brain.

Authors:  A Ludwig; V Flockerzi; F Hofmann
Journal:  J Neurosci       Date:  1997-02-15       Impact factor: 6.167

2.  Stable co-expression of calcium channel alpha 1, beta and alpha 2/delta subunits in a somatic cell line.

Authors:  A Welling; E Bosse; A Cavalié; R Bottlender; A Ludwig; W Nastainczyk; V Flockerzi; F Hofmann
Journal:  J Physiol       Date:  1993-11       Impact factor: 5.182

3.  Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line.

Authors:  R G Smith; M E Alexianu; G Crawford; O Nyormoi; E Stefani; S H Appel
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-12       Impact factor: 11.205

4.  Expression of the L-type calcium channel with two different beta subunits and its modulation by Ro 40-5967.

Authors:  A Welling; L Lacinova; K Donatin; A Ludwig; E Bosse; V Flockerzi; F Hofmann
Journal:  Pflugers Arch       Date:  1995-01       Impact factor: 3.657

5.  Full-length myotonin protein kinase (72 kDa) displays serine kinase activity.

Authors:  L Timchenko; W Nastainczyk; T Schneider; B Patel; F Hofmann; C T Caskey
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205

  5 in total

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