Literature DB >> 21770172

Label free DNA detection using large area graphene based field effect transistor biosensors.

Shi-Rui Guo1, Jian Lin, Miroslav Penchev, Emre Yengel, Maziar Ghazinejad, Cengiz S Ozkan, Mihrimah Ozkan.   

Abstract

We describe the fabrication of highly sensitive graphene based field effect transistor (FET) biosensors with a cost-effective approach and their application in label-free Deoxyribonucleic acid (DNA) detection. Chemical vapor deposition (CVD) grown graphene layers were used to achieve mass production of FET devices via conventional photolithographic patterning. Non-covalent functionalization of the graphene layer with 1-Pyrenebutanoic acid succinimidyl ester ensures high conductivity and sensitivity of the FET device. The present device could reach a detection limit as low as 3 x 10(-9) M.

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Year:  2011        PMID: 21770172     DOI: 10.1166/jnn.2011.3885

Source DB:  PubMed          Journal:  J Nanosci Nanotechnol        ISSN: 1533-4880


  6 in total

1.  Reusable resistive aptasensor for Pb(II) based on the Pb(II)-induced despiralization of a DNA duplex and formation of a G-quadruplex.

Authors:  Hui Wang; Yang Liu; Gang Liu
Journal:  Mikrochim Acta       Date:  2018-01-29       Impact factor: 5.833

Review 2.  Plasma-Enabled Carbon Nanostructures for Early Diagnosis of Neurodegenerative Diseases.

Authors:  Shafique Pineda; Zhao Jun Han; Kostya Ostrikov
Journal:  Materials (Basel)       Date:  2014-06-25       Impact factor: 3.623

3.  Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor.

Authors:  Shicai Xu; Jian Zhan; Baoyuan Man; Shouzhen Jiang; Weiwei Yue; Shoubao Gao; Chengang Guo; Hanping Liu; Zhenhua Li; Jihua Wang; Yaoqi Zhou
Journal:  Nat Commun       Date:  2017-03-21       Impact factor: 14.919

4.  Chemically Functionalised Graphene FET Biosensor for the Label-free Sensing of Exosomes.

Authors:  Deana Kwong Hong Tsang; Tyler J Lieberthal; Clare Watts; Iain E Dunlop; Sami Ramadan; Armando E Del Rio Hernandez; Norbert Klein
Journal:  Sci Rep       Date:  2019-09-26       Impact factor: 4.379

Review 5.  Graphene, an Interesting Nanocarbon Allotrope for Biosensing Applications: Advances, Insights, and Prospects.

Authors:  Farid Menaa; Yazdian Fatemeh; Sandeep K Vashist; Haroon Iqbal; Olga N Sharts; Bouzid Menaa
Journal:  Biomed Eng Comput Biol       Date:  2021-02-24

6.  Real-time label-free detection of DNA hybridization using a functionalized graphene field effect transistor: a theoretical study.

Authors:  Sheida Bagherzadeh-Nobari; Reza Kalantarinejad
Journal:  J Nanopart Res       Date:  2021-08-16       Impact factor: 2.253

  6 in total

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