Literature DB >> 21769413

Bioluminescent stem-loop probes for highly sensitive nucleic acid detection.

Eric A Hunt1, Sapna K Deo.   

Abstract

Here, we report the first bioluminescent stem-loop probe, which is 50 times more sensitive and able to achieve a LOD 25 times lower than fluorescent stem-loop probes. Chemical generation of a signal from Renilla luciferase reduces background noise for improved quantitative utility in nucleic acid biomarker detection. This journal is © The Royal Society of Chemistry 2011

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Year:  2011        PMID： 21769413     DOI： 10.1039/c1cc13495g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Expression of a soluble truncated Vargula luciferase in Escherichia coli.

Authors:  Eric A Hunt; Angeliki Moutsiopoulou; David Broyles; Trajen Head; Emre Dikici; Sylvia Daunert; Sapna K Deo
Journal:  Protein Expr Purif       Date:  2017-01-18       Impact factor: 1.650

2.  Using commercially available personal glucose meters for portable quantification of DNA.

Authors:  Yu Xiang; Yi Lu
Journal:  Anal Chem       Date:  2012-02-06       Impact factor: 6.986

Review 3.  Molecular Aptamer Beacons and Their Applications in Sensing, Imaging, and Diagnostics.

Authors:  Angeliki Moutsiopoulou; David Broyles; Emre Dikici; Sylvia Daunert; Sapna K Deo
Journal:  Small       Date:  2019-07-17       Impact factor: 13.281

4.  Enzymatic Beacons for Specific Sensing of Dilute Nucleic Acid.

Authors:  Xiaoyu Zhang; Venubabu Kotikam; Eriks Rozners; Brian P Callahan
Journal:  Chembiochem       Date:  2021-12-29       Impact factor: 3.164

5.  Bioluminescent Protein-Inhibitor Pair in the Design of a Molecular Aptamer Beacon Biosensing System.

Authors:  Angeliki Moutsiopoulou; David Broyles; Hamdi Joda; Emre Dikici; Avinash Kaur; Angel Kaifer; Sylvia Daunert; Sapna K Deo
Journal:  Anal Chem       Date:  2020-05-21       Impact factor: 6.986

6.  Truncated Variants of Gaussia Luciferase with Tyrosine Linker for Site-Specific Bioconjugate Applications.

Authors:  Eric A Hunt; Angeliki Moutsiopoulou; Stephanie Ioannou; Katelyn Ahern; Kristen Woodward; Emre Dikici; Sylvia Daunert; Sapna K Deo
Journal:  Sci Rep       Date:  2016-06-08       Impact factor: 4.379

7.  Nucleic acid detection using BRET-beacons based on bioluminescent protein-DNA hybrids.

Authors:  Wouter Engelen; Kayleigh M van de Wiel; Lenny H H Meijer; Bedabrata Saha; Maarten Merkx
Journal:  Chem Commun (Camb)       Date:  2017-03-02       Impact factor: 6.222

8.  Enzymatic Beacons for Specific Sensing of Dilute Nucleic Acid and Potential Utility for SARS-CoV-2 Detection.

Authors:  Xiaoyu Zhang; Venubabu Kotikam; Eriks Rozners; Brian P Callahan
Journal:  bioRxiv       Date:  2021-08-31
  8 in total

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