| Literature DB >> 21769329 |
Sascha Hoogendoorn1, Kim L Habets, Solène Passemard, Johan Kuiper, Gijsbert A van der Marel, Bogdan I Florea, Herman S Overkleeft.
Abstract
Bifunctional, pH-activatable BODIPY dyes were developed and incorporated in mannose cluster-containing activity-based probes for cysteine proteases. Mannose receptor-dependent uptake of the probes in dendritic cells, followed by trafficking to acidic cellular compartments resulted in fluorescence as seen by live-cell imaging, and subsequent cathepsin inhibition. This journal is © The Royal Society of Chemistry 2011Entities:
Mesh：
Substances：
Year: 2011 PMID： 21769329 DOI： 10.1039/c1cc12947c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222