Literature DB >> 21768897

The development of a urinary tract infection is associated with increased mortality in trauma patients.

Sean F Monaghan1, Daithi S Heffernan, Rajan K Thakkar, Steven E Reinert, Jason T Machan, Michael D Connolly, Shea C Gregg, Matthew S Kozloff, Charles A Adams, William G Cioffi.   

Abstract

BACKGROUND: In October 2008, Medicare and Medicaid stopped paying for care associated with catheter-related urinary tract infections (UTIs). Although most clinicians agree UTIs are detrimental, there are little data to support this belief.
METHODS: This is a retrospective review of trauma registry data from a Level I trauma center between 2003 and 2008. Two proportional hazards regressions were used for analyses. The first predicted acquisition of UTI as a function of indwelling urinary catheter use, adjusting for age, diabetes, gender, and injury severity. The second predicted hospital mortality as a function of UTI, covarying for age, gender, chronic obstructive pulmonary disease, congestive heart failure, hypertension, diabetes, pneumonia, and injury severity.
RESULTS: After excluding patients who stayed in the hospital <3 days and those with a UTI on arrival, 5,736 patients were included in the study. Of these patients, 680 (11.9%) met criteria for a UTI, with 487 (71.6%) indwelling urinary catheter-related infections. Predictors of UTI included the interaction between age and gender (p = 0.0018), Injury Severity Score (p = 0.0021), and indwelling urinary catheter use (p < 0.001). The development of a UTI predicted the risk of in-hospital death as a patient's age increased (p = 0.002). Similar results were seen when only catheter-associated UTIs are included in the analysis.
CONCLUSIONS: Indwelling urinary catheter use is connected to the development of UTIs, and these infections are associated with a greater mortality as the age of a trauma patients increases.

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Year:  2011        PMID: 21768897     DOI: 10.1097/TA.0b013e31821e2b8f

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  2 in total

1.  Nosocomial infection in trauma intensive care.

Authors:  Jonathan Stephen Major; Jessie Welbourne
Journal:  J Intensive Care Soc       Date:  2015-07-23

2.  Clinical outcomes of hospitalised patients with catheter-associated urinary tract infection in countries with a high rate of multidrug-resistance: the COMBACTE-MAGNET RESCUING study.

Authors:  Aina Gomila; Jordi Carratalà; Noa Eliakim-Raz; Evelyn Shaw; Cristian Tebé; Martin Wolkewitz; Irith Wiegand; Sally Grier; Christiane Vank; Nienke Cuperus; Leonard Van den Heuvel; Cuong Vuong; Alasdair MacGowan; Leonard Leibovici; Ibironke Addy; Miquel Pujol
Journal:  Antimicrob Resist Infect Control       Date:  2019-12-03       Impact factor: 4.887

  2 in total

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