| Literature DB >> 21766884 |
Shi-Yie Cheng1, Chao-Min Wang, Yuan-Man Hsu, Tsurng-Juhn Huang, Shen-Chieh Chou, En-Hung Lin, Chang-Hung Chou.
Abstract
Seven new oleanane-type triterpenoids (1-7), named fatsicarpains A-G, and the known compounds 3α-hydroxyolean-11,13(18)-dien-28-oic acid (8) and 3α-hydroxyolean-11-en-28,13β-olide (9) were isolated from the leaves and twigs of Fatsia polycarpa on the basis of bioassay-guided fractionation. The structures of compounds 1-7 were elucidated through spectroscopic analyses and single-crystal X-ray crystallography of 1, 8, and 9. Cytotoxicity against HepG2 2.2.15 and AGS cells and antihepatitis B virus (HBV) and antibacterial activities of 1-9 were also evaluated in vitro.Entities:
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Year: 2011 PMID： 21766884 DOI： 10.1021/np2002435
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050