Literature DB >> 21766410

Vascular targeting of antithrombotic agents.

Ronald Carnemolla1, Vladimir R Muzykantov.   

Abstract

In this review we discuss the limited efficacy for current pharmacological agents used in prophylaxis and treatment of thrombosis and highlight targeted delivery of anti-thrombotic agents to fibrin, platelets, red blood cells and endothelium.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID： 21766410      PMCID： PMC3298751          DOI： 10.1002/iub.474

Source DB:  PubMed          Journal:  IUBMB Life        ISSN： 1521-6543            Impact factor:   3.885


  48 in total

1.  Distributed intraclot thrombolysis: mechanism of accelerated thrombolysis with encapsulated plasminogen activators.

Authors:  J K Leach; E Patterson; E A O'Rear
Journal:  J Thromb Haemost       Date:  2004-09       Impact factor: 5.824

2.  Blood clearance and activity of erythrocyte-coupled fibrinolytics.

Authors:  Kumkum Ganguly; Tatiana Krasik; Sandra Medinilla; Khalil Bdeir; Douglas B Cines; Vladimir R Muzykantov; Juan Carlos Murciano
Journal:  J Pharmacol Exp Ther       Date:  2004-11-03       Impact factor: 4.030

3.  Fibrin affinity of erythrocyte-coupled tissue-type plasminogen activators endures hemodynamic forces and enhances fibrinolysis in vivo.

Authors:  Kumkum Ganguly; Mukul S Goel; Tatyana Krasik; Khalil Bdeir; Scott L Diamond; Douglas B Cines; Vladimir R Muzykantov; Juan-Carlos Murciano
Journal:  J Pharmacol Exp Ther       Date:  2005-11-11       Impact factor: 4.030

Review 4.  New anti-thrombotic agents: emphasis on hemorrhagic complications and their management.

Authors:  Heng Joo Ng; Mark A Crowther
Journal:  Semin Hematol       Date:  2006-01       Impact factor: 3.851

5.  Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature.

Authors:  Bi-Sen Ding; Claudia Gottstein; Andrea Grunow; Alice Kuo; Kumkum Ganguly; Steven M Albelda; Douglas B Cines; Vladimir R Muzykantov
Journal:  Blood       Date:  2005-09-06       Impact factor: 22.113

6.  Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1.

Authors:  Silvia Muro; Thomas Dziubla; Weining Qiu; John Leferovich; Xiumin Cui; Erik Berk; Vladimir R Muzykantov
Journal:  J Pharmacol Exp Ther       Date:  2006-02-27       Impact factor: 4.030

7.  Fibrin-targeted perfluorocarbon nanoparticles for targeted thrombolysis.

Authors:  J N Marsh; A Senpan; G Hu; M J Scott; P J Gaffney; S A Wickline; G M Lanza
Journal:  Nanomedicine (Lond)       Date:  2007-08       Impact factor: 5.307

8.  Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator.

Authors:  Kristina Danielyan; Kumkum Ganguly; Bi-Sen Ding; Dmitriy Atochin; Sergei Zaitsev; Juan-Carlos Murciano; Paul L Huang; Scott E Kasner; Douglas B Cines; Vladimir R Muzykantov
Journal:  Circulation       Date:  2008-09-15       Impact factor: 29.690

9.  The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator.

Authors:  Ji-Young Kim; Jin-Ki Kim; Jeong-Sook Park; Youngro Byun; Chong-Kook Kim
Journal:  Biomaterials       Date:  2009-08-04       Impact factor: 12.479

10.  Erythrocyte-bound tissue plasminogen activator is neuroprotective in experimental traumatic brain injury.

Authors:  Sherman C Stein; Kumkum Ganguly; Caitlin M Belfield; Xiangsheng Xu; Edward W Swanson; Xiao-Han Chen; Kevin D Browne; Victoria E Johnson; Douglas H Smith; David G LeBold; Douglas B Cines; Vladimir R Muzykantov; Vladimir R Muzykhantov
Journal:  J Neurotrauma       Date:  2009-09       Impact factor: 5.269
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  4 in total

Review 1.  Advanced drug delivery systems for antithrombotic agents.

Authors:  Colin F Greineder; Melissa D Howard; Ronald Carnemolla; Douglas B Cines; Vladimir R Muzykantov
Journal:  Blood       Date:  2013-06-24       Impact factor: 22.113

2.  Fibrin-specific poly(N-isopropylacrylamide) nanogels for targeted delivery of tissue-type plasminogen activator to treat thrombotic complications are well tolerated in vivo.

Authors:  Emily P Mihalko; Kimberly Nellenbach; Manasi Krishnakumar; Nina Moiseiwitsch; Jennifer Sollinger; Brian C Cooley; Ashley C Brown
Journal:  Bioeng Transl Med       Date:  2021-12-11

3.  Elongated Plant Virus-Based Nanoparticles for Enhanced Delivery of Thrombolytic Therapies.

Authors:  Andrzej S Pitek; Yunmei Wang; Sahil Gulati; Huiyun Gao; Phoebe L Stewart; Daniel I Simon; Nicole F Steinmetz
Journal:  Mol Pharm       Date:  2017-09-26       Impact factor: 4.939

4.  Mechanism of Collaborative Enhancement of Binding of Paired Antibodies to Distinct Epitopes of Platelet Endothelial Cell Adhesion Molecule-1.

Authors:  Raisa Kiseleva; Colin F Greineder; Carlos H Villa; Elizabeth D Hood; Vladimir V Shuvaev; Jing Sun; Ann-Marie Chacko; Valsamma Abraham; Horace M DeLisser; Vladimir R Muzykantov
Journal:  PLoS One       Date:  2017-01-13       Impact factor: 3.240
  4 in total

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