Literature DB >> 21766403

Inhibitors of the herbicidal target IspD: allosteric site binding.

Matthias C Witschel1, H Wolfgang Höffken, Michael Seet, Liliana Parra, Thomas Mietzner, Frank Thater, Ricarda Niggeweg, Franz Röhl, Boris Illarionov, Felix Rohdich, Johannes Kaiser, Markus Fischer, Adelbert Bacher, François Diederich.   

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Year:  2011        PMID： 21766403     DOI： 10.1002/anie.201102281

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  14 in total

1.  A chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesis.

Authors:  Wesley Wu; Zachary Herrera; Danny Ebert; Katie Baska; Seok H Cho; Joseph L DeRisi; Ellen Yeh
Journal:  Antimicrob Agents Chemother       Date:  2014-11-03       Impact factor: 5.191

Review 2.  Mechanistic aspects of carotenoid biosynthesis.

Authors:  Alexander R Moise; Salim Al-Babili; Eleanore T Wurtzel
Journal:  Chem Rev       Date:  2013-10-31       Impact factor: 60.622

3.  A high-throughput screening campaign to identify inhibitors of DXP reductoisomerase (IspC) and MEP cytidylyltransferase (IspD).

Authors:  Amanda Haymond; Tyrone Dowdy; Chinchu Johny; Claire Johnson; Haley Ball; Allyson Dailey; Brandon Schweibenz; Karen Villarroel; Richard Young; Clark J Mantooth; Trishal Patel; Jessica Bases; Cynthia S Dowd; Robin D Couch
Journal:  Anal Biochem       Date:  2017-11-24       Impact factor: 3.365

4.  Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target.

Authors:  Leah S Imlay; Christopher M Armstrong; Mary Clare Masters; Ting Li; Kathryn E Price; Rachel L Edwards; Katherine M Mann; Lucy X Li; Christina L Stallings; Neil G Berry; Paul M O'Neill; Audrey R Odom
Journal:  ACS Infect Dis       Date:  2015-03-02       Impact factor: 5.084

5.  Deciphering structure, function and mechanism of Plasmodium IspD homologs from their evolutionary imprints.

Authors:  P Chellapandi; R Prathiviraj; A Prisilla
Journal:  J Comput Aided Mol Des       Date:  2019-02-19       Impact factor: 3.686

6.  Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens.

Authors:  Sergiy G Krasutsky; Marek Urbansky; Chad E Davis; Christian Lherbet; Robert M Coates; C Dale Poulter
Journal:  J Org Chem       Date:  2014-09-23       Impact factor: 4.354

7.  A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.

Authors:  Yun Jin; Zhongchuan Liu; Yanjie Li; Weifeng Liu; Yong Tao; Ganggang Wang
Journal:  Sci Rep       Date:  2016-11-08       Impact factor: 4.379

8.  Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD.

Authors:  Kathryn E Price; Christopher M Armstrong; Leah S Imlay; Dana M Hodge; C Pidathala; Natalie J Roberts; Jooyoung Park; Marwa Mikati; Raman Sharma; Alexandre S Lawrenson; Niraj H Tolia; Neil G Berry; Paul M O'Neill; Audrey R Odom John
Journal:  Sci Rep       Date:  2016-11-18       Impact factor: 4.379

9.  Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase).

Authors:  Amanda Haymond; Chinchu Johny; Tyrone Dowdy; Brandon Schweibenz; Karen Villarroel; Richard Young; Clark J Mantooth; Trishal Patel; Jessica Bases; Geraldine San Jose; Emily R Jackson; Cynthia S Dowd; Robin D Couch
Journal:  PLoS One       Date:  2014-08-29       Impact factor: 3.240

Review 10.  New Insight into Isoprenoids Biosynthesis Process and Future Prospects for Drug Designing in Plasmodium.

Authors:  Gagandeep S Saggu; Zarna R Pala; Shilpi Garg; Vishal Saxena
Journal:  Front Microbiol       Date:  2016-09-13       Impact factor: 5.640
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