Literature DB >> 21765687

Minimally invasive parathyroid surgery.

G M Fuhrman1, J S Bolton.   

Abstract

Minimally invasive parathyroidectomy offers patients a less morbid surgical approach to treat primary hyperparathyroidism. Biochemically diagnosed hyperparathyroid patients undergo a preoperative sestamibi scan to localize abnormal parathyroid tissue. If the scan is positive, a focused unilateral neck exploration is performed through a 2-3 cm incision with the aid of a gamma detector to identify the radioactive, abnormal parathyroid gland(s).In the Ochsner Clinic's initial experience with minimally invasive parathyroidectomy, 34 patients were evaluated with 20 positive scans, 4 suggestive scans, and 10 negative scans. Of the 24 patients with scans demonstrating abnormal parathyroid activity, 23 were successfully managed with the minimally invasive technique. The mean total surgical time was 72.9 minutes, and the mean weight of the excised parathyroid glands was 1445.4 mg. All 10 patients with negative scans had a traditional bilateral neck exploration lasting a mean time of 146.5 minutes; the mean weight of the excised parathyroid glands was 388.6 mg. Hypercalcemia was cured in all 24 patients in the positive group and 9 of 10 patients in the negative scan group.Ochsner's initial experience with minimally invasive parathyroidectomy demonstrates that about 70% of patients can expect to be candidates for this technique, which is associated with excellent cure rates and shorter operative times.

Entities:  

Year:  2000        PMID: 21765687      PMCID: PMC3117524     

Source DB:  PubMed          Journal:  Ochsner J        ISSN: 1524-5012


  13 in total

1.  Minimally invasive parathyroidectomy utilizing a gamma detecting probe intraoperatively.

Authors:  J A Singer; A Sardi; G Conaway; E J Spiegler
Journal:  Md Med J       Date:  1999 Mar-Apr

2.  The 20% rule: a simple, instantaneous radioactivity measurement defines cure and allows elimination of frozen sections and hormone assays during parathyroidectomy.

Authors:  C Murphy; J Norman
Journal:  Surgery       Date:  1999-12       Impact factor: 3.982

3.  Outpatient minimally invasive parathyroidectomy: a combination of sestamibi-SPECT localization, cervical block anesthesia, and intraoperative parathyroid hormone assay.

Authors:  H Chen; L J Sokoll; R Udelsman
Journal:  Surgery       Date:  1999-12       Impact factor: 3.982

4.  Bilateral neck exploration for parathyroidectomy under local anesthesia: a viable technique for patients with coexisting thyroid disease with or without sestamibi scanning.

Authors:  P Lo Gerfo
Journal:  Surgery       Date:  1999-12       Impact factor: 3.982

Review 5.  Radionuclide scanning in parathyroid diseases.

Authors:  F Pattou; D Huglo; C Proye
Journal:  Br J Surg       Date:  1998-12       Impact factor: 6.939

Review 6.  Complications of surgery of the thyroid and parathyroid glands.

Authors:  M P Kahky; R S Weber
Journal:  Surg Clin North Am       Date:  1993-04       Impact factor: 2.741

Review 7.  Parathyroid autotransplantation.

Authors:  D S Baumann; S A Wells
Journal:  Surgery       Date:  1993-02       Impact factor: 3.982

8.  Parathyroid localization with high-resolution ultrasound and technetium Tc 99m sestamibi.

Authors:  G P Purcell; F M Dirbas; R B Jeffrey; M J Lane; T Desser; I R McDougall; R J Weigel
Journal:  Arch Surg       Date:  1999-08

9.  Total parathyroidectomy and autotransplantation in hyperplasia of the parathyroid gland.

Authors:  A D Harding; W K Nichols; F L Mitchell
Journal:  Surg Gynecol Obstet       Date:  1990-10

10.  Parathyroidectomy via bilateral cervical exploration: a retrospective review of 866 cases.

Authors:  R A Low; A D Katz
Journal:  Head Neck       Date:  1998-10       Impact factor: 3.147

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