Literature DB >> 2176524

Alterations of neuroreceptors in nasal hyperreactivity.

Y J van Megen1, J F Rodrigues de Miranda, A B Klaassen.   

Abstract

Cholinergic and adrenergic abnormalities have been observed in nasal allergy and may be due to changes in pharmacological characteristics of neuroreceptors. Radioligand receptor binding studies demonstrated no significant changes in affinities or densities of alpha-adrenoceptors, a decreased number of beta-adrenoceptors and a decreased affinity combined with a decreased number of muscarinic acetylcholine receptors.

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Year:  1990        PMID： 2176524      PMCID： PMC1368124          DOI： 10.1111/j.1365-2125.1990.tb05494.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  7 in total

1.  Nasal airway response to infused phenylephrine in normals and in patients with allergic and non-allergic rhinitis.

Authors:  C D Brooks; G C Spenner; K J Karl; C T Heissler; C M Metzler
Journal:  Rhinology       Date:  1988-03       Impact factor: 3.681

2.  Demonstration of alpha 1-adrenoceptors in rat nasal mucosa.

Authors:  Y J van Megen; A B Klaassen; J F Rodrigues de Miranda; R T Wentges; C A van Ginneken
Journal:  J Recept Res       Date:  1989

Review 3.  Neural control of human airways in health and disease.

Authors:  P J Barnes
Journal:  Am Rev Respir Dis       Date:  1986-12

Review 4.  Mediators of nasal allergy.

Authors:  N Mygind
Journal:  J Allergy Clin Immunol       Date:  1982-09       Impact factor: 10.793

5.  Characterization of beta-adrenoceptor subtypes in rat kidney with new highly selective beta 1 blockers and their role in renin release.

Authors:  M Milavec-Krizman; J P Evenou; H Wagner; R Berthold; A P Stoll
Journal:  Biochem Pharmacol       Date:  1985-11-15       Impact factor: 5.858

6.  Muscarinic receptors in rat nasal mucosa are predominantly of the low affinity agonist type.

Authors:  J F Rodrigues de Miranda; H M Scheres; H J Salden; A J Beld; A B Klaassen; W Kuijpers
Journal:  Eur J Pharmacol       Date:  1985-07-31       Impact factor: 4.432

7.  Abnormal beta-adrenergic responsiveness in allergic subjects. II. The role of selective beta 2-adrenergic hyporeactivity.

Authors:  J H Shelhamer; Z Marom; M Kaliner
Journal:  J Allergy Clin Immunol       Date:  1983-01       Impact factor: 10.793
  7 in total
  1 in total

1.  Role of parasympathetic nerves and muscarinic receptors in allergy and asthma.

Authors:  Gregory D Scott; Allison D Fryer
Journal:  Chem Immunol Allergy       Date:  2012-06-26
  1 in total

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