Literature DB >> 2176448

Effect of aflatoxins on rat peritoneal macrophages.

V Cusumano1, G B Costa, S Seminara.   

Abstract

Phagocytosis, intracellular killing of Candida albicans, and superoxide production by rat peritoneal macrophages exposed to aflatoxins B1, B2, G1, G2, B2a, and M1 at several times and concentrations were analyzed to evaluate the intensity of a depressive effect for each mycotoxin. All aflatoxins used at very low concentrations had a depressive effect on the functions of macrophages. The biggest impairment of phagocytosis, intracellular killing, and spontaneous superoxide production was observed in macrophages exposed to aflatoxins B1 and M1.

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Year:  1990        PMID： 2176448      PMCID： PMC184993          DOI： 10.1128/aem.56.11.3482-3484.1990

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  14 in total

1.  Effect of aflatoxin on the humoral and cell-mediated immune systems of the chicken.

Authors:  J J Giambrone; D L Ewert; R D Wyatt; C S Eidson
Journal:  Am J Vet Res       Date:  1978-02       Impact factor: 1.156

2.  Impairment of the reticuloendothelial system of chickens during aflatoxicosis.

Authors:  G Y Michael; P Thaxton; P B Hamilton
Journal:  Poult Sci       Date:  1973-05       Impact factor: 3.352

3.  Refractory phagocytosis by chicken thrombocytes during aflatoxicosis.

Authors:  C F Chang; P B Hamilton
Journal:  Poult Sci       Date:  1979-05       Impact factor: 3.352

4.  Impairment of phagocytosis in chicken monocytes during aflatoxicosis.

Authors:  C F Chang; P B Hamilton
Journal:  Poult Sci       Date:  1979-05       Impact factor: 3.352

5.  Effect of aflatoxin on phagocytosis of Aspergillus fumigatus spores by rabbit alveolar macrophages.

Authors:  J L Richard; J R Thurston
Journal:  Appl Microbiol       Date:  1975-07

6.  Effect of T-2 toxin on adrenocortical function and immune response in growing pigs.

Authors:  P Rafai; S Tuboly
Journal:  Zentralbl Veterinarmed B       Date:  1982-08

7.  Impaired phagocytosis by heterophils from chickens during aflatoxicosis.

Authors:  C F Chang; P B Hamilton
Journal:  Toxicol Appl Pharmacol       Date:  1979-05       Impact factor: 4.219

8.  Effect of ochratoxin and aflatoxin on serum proteins, complement activity, and antibody production to Brucella abortus in guinea pigs.

Authors:  J L Richard; J R Thurston; B L Deyoe; G D Booth
Journal:  Appl Microbiol       Date:  1975-01

9.  A rapid micro method for the simultaneous determination of phagocytic-microbiocidal activity of human peripheral blood leukocytes in vitro.

Authors:  D L Smith; F Rommel
Journal:  J Immunol Methods       Date:  1977       Impact factor: 2.303

10.  Superoxide production by phagocytic leukocytes.

Authors:  D B Drath; M L Karnovsky
Journal:  J Exp Med       Date:  1975-01-01       Impact factor: 14.307
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  7 in total

1.  The cytotoxicity of aflatoxin b1 in human lymphocytes.

Authors:  Suleiman Al-Hammadi; Farida Marzouqi; Aysha Al-Mansouri; Allen Shahin; Mariam Al-Shamsi; Eric Mensah-Brown; Abdul-Kader Souid
Journal:  Sultan Qaboos Univ Med J       Date:  2014-01-27

2.  Role of germination in murine airway CD8+ T-cell responses to Aspergillus conidia.

Authors:  Steven P Templeton; Amanda D Buskirk; Brandon Law; Brett J Green; Donald H Beezhold
Journal:  PLoS One       Date:  2011-04-13       Impact factor: 3.240

3.  A Protective Mechanism in Lungs of Rats Experimentally Infected with Aspergillus fumigatus.

Authors:  Yehia A-G Mahmoud; Abdulaziz Yahya Al-Ghamdi; Eman H F Abd El-Zaher
Journal:  Mycobiology       Date:  2011-03-23       Impact factor: 1.858

Review 4.  Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action.

Authors:  Noreddine Benkerroum
Journal:  Int J Environ Res Public Health       Date:  2020-01-08       Impact factor: 3.390

Review 5.  Metabolic Disruption by Naturally Occurring Mycotoxins in Circulation: A Focus on Vascular and Bone Homeostasis Dysfunction.

Authors:  Amir Mohammad Malvandi; Sara Shahba; Jalil Mehrzad; Giovanni Lombardi
Journal:  Front Nutr       Date:  2022-06-24

6.  Transcriptional Profiling of Aflatoxin B1-Induced Oxidative Stress and Inflammatory Response in Macrophages.

Authors:  Jinglin Ma; Yanrong Liu; Yongpeng Guo; Qiugang Ma; Cheng Ji; Lihong Zhao
Journal:  Toxins (Basel)       Date:  2021-06-04       Impact factor: 4.546

Review 7.  Molecular Insights Into Development and Virulence Determinants of Aspergilli: A Proteomic Perspective.

Authors:  Jata Shankar; Shraddha Tiwari; Sonia K Shishodia; Manali Gangwar; Shanu Hoda; Raman Thakur; Pooja Vijayaraghavan
Journal:  Front Cell Infect Microbiol       Date:  2018-05-29       Impact factor: 5.293
  7 in total

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