Literature DB >> 21764450

Possibility of myelodysplastic syndromes screening using a complete blood automated cell count.

Vincenzo Rocco1, Mariacaterina Maconi, Maria Gioia, Maria Grazia Silvestri, Donatella Tanca, Teodora Catalano, Daniela Avino, Anna Di Palma, Adele Rovetti, Paolo Danise.   

Abstract

Diagnosis of MDS has changed during the last years because of the 2008 WHO classification. Complete blood cell count (CBC) is a very important tool both for diagnosis of MDS. The aim of this study was to evaluate if it is possible to use the abnormal signals produced by dysplastic cells to produce a flag "dysplasia" able to identify the patients needing further hematological investigations. The proposed flag has been tested in a large group of patients to evaluate the sensibility and specificity. We create 5 patterns of MDS. Our study demonstrated that the flag "dysplasia" is specific and sensible for MDS. Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21764450     DOI: 10.1016/j.leukres.2011.06.015

Source DB:  PubMed          Journal:  Leuk Res        ISSN: 0145-2126            Impact factor:   3.156


  1 in total

1.  Mean platelet component and mean platelet volume as useful screening markers for myelodysplastic syndrome.

Authors:  Ryota Masutani; Toshiyuki Ikemoto; Ayako Maki; Hiroko Tanada; Yoshinori Iwatani; Mikio Watanabe; Takayuki Takubo; Yoshikatsu Okada
Journal:  Health Sci Rep       Date:  2018-05-02
  1 in total

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