| Literature DB >> 21763972 |
Patricia A Tang1, Michael M Vickers, Daniel Y C Heng.
Abstract
The current treatment paradigm for metastatic renal cell carcinoma (RCC) includes agents that target the vascular endothelial growth factor (VEGF) and mammalian target of rapamycin (mTOR) pathways. Because these agents have revolutionized RCC over the past five years, new clinical and molecular predictive and prognostic tools are required. These are potentially important for therapy selection, patient counseling, and clinical trial stratification. This review examines clinical prognostic models and molecular biomarkers in RCC.Entities:
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Year: 2011 PMID: 21763972 DOI: 10.1016/j.hoc.2011.04.003
Source DB: PubMed Journal: Hematol Oncol Clin North Am ISSN: 0889-8588 Impact factor: 3.722