Literature DB >> 21763601

Enhancers: from developmental genetics to the genetics of common human disease.

Iain Williamson1, Robert E Hill, Wendy A Bickmore.   

Abstract

In mammals, long-range gene regulation became apparent through simple Mendelian disease genetics in human and developmental genetics in the mouse. Can the insights into gene control, provided by the study of these enhancers, help us understand the functional significance of sequence variation associated with common/complex human disease and quantitative traits?
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21763601     DOI： 10.1016/j.devcel.2011.06.008

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  29 in total

1.  Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus.

Authors:  Kerstin Hasenpusch-Theil; Dario Magnani; Eleni-Maria Amaniti; Lin Han; Douglas Armstrong; Thomas Theil
Journal:  Cereb Cortex       Date:  2012-01-10       Impact factor: 5.357

2.  Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci.

Authors:  Karsten B Sieber; Anna Batorsky; Kyle Siebenthall; Kelly L Hudkins; Jeff D Vierstra; Shawn Sullivan; Aakash Sur; Michelle McNulty; Richard Sandstrom; Alex Reynolds; Daniel Bates; Morgan Diegel; Douglass Dunn; Jemma Nelson; Michael Buckley; Rajinder Kaul; Matthew G Sampson; Jonathan Himmelfarb; Charles E Alpers; Dawn Waterworth; Shreeram Akilesh
Journal:  J Am Soc Nephrol       Date:  2019-02-13       Impact factor: 10.121

Review 3.  From remote enhancers to gene regulation: charting the genome's regulatory landscapes.

Authors:  Orsolya Symmons; François Spitz
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-05-06       Impact factor: 6.237

4.  Global view of enhancer-promoter interactome in human cells.

Authors:  Bing He; Changya Chen; Li Teng; Kai Tan
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-12       Impact factor: 11.205

Review 5.  In pursuit of design principles of regulatory sequences.

Authors:  Michal Levo; Eran Segal
Journal:  Nat Rev Genet       Date:  2014-06-10       Impact factor: 53.242

6.  Chromatin Conformation Links Distal Target Genes to CKD Loci.

Authors:  Maarten M Brandt; Claartje A Meddens; Laura Louzao-Martinez; Noortje A M van den Dungen; Nico R Lansu; Edward E S Nieuwenhuis; Dirk J Duncker; Marianne C Verhaar; Jaap A Joles; Michal Mokry; Caroline Cheng
Journal:  J Am Soc Nephrol       Date:  2017-11-01       Impact factor: 10.121

7.  DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics.

Authors:  Yoon Jeong Park; Sangseon Lee; Sangsoo Lim; Hahn Nahmgoong; Yul Ji; Jin Young Huh; Assim A Alfadda; Sun Kim; Jae Bum Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2021-03-16       Impact factor: 11.205

Review 8.  Enhancers as information integration hubs in development: lessons from genomics.

Authors:  Christa Buecker; Joanna Wysocka
Journal:  Trends Genet       Date:  2012-04-07       Impact factor: 11.639

9.  Identification of a face enhancer reveals direct regulation of LIM homeobox 8 (Lhx8) by wingless-int (WNT)/β-catenin signaling.

Authors:  André Landin Malt; Jeffry M Cesario; Zuojian Tang; Stuart Brown; Juhee Jeong
Journal:  J Biol Chem       Date:  2014-09-04       Impact factor: 5.157

10.  Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region.

Authors:  Phillip W L Tai; Hai Wu; Jonathan A R Gordon; Troy W Whitfield; A Rasim Barutcu; André J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein
Journal:  Gene       Date:  2014-06-02       Impact factor: 3.688
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