OBJECTIVE: To study the chemical constituents of Abelmoschus esculentus. METHOD: The chemical constituents were isolated and purified by chromatography on silica gel and recrystallization. The chemical structures were elucidated on the basis of physicochemical properties and spectral data. RESULT: Fourteen compounds were isolated and identified as 6-hydroxy-stigmasta-4-en-3-one(1), 6-hydroxy-stigmasta4,22-dien-3-one(2), stigmasta-5-en-3-ol-7-one(3), stigmasta-5, 22-dien-3-ol-7-one(4), stigmast-5-en-3, 7-diol(5), stigmast-5, 22-dien-3, 7-diol(6), stigmast-4, 22-dien-3, 6-dione(7), stigmasta-4, 22-dien-3-one(8), ergosta-7, 22-dien-3-ol(9), cycloart-25-en-3,24-diol(10), lupeol(11), aurantiamide acetate (12), stigmasterol(13), hexadecanoic acid (14). CONCLUSION: Compounds 1-12 are obtained from the genus Abelmoschus plant for the first time and also from the Malvaceae for the first time.
OBJECTIVE: To study the chemical constituents of Abelmoschus esculentus. METHOD: The chemical constituents were isolated and purified by chromatography on silica gel and recrystallization. The chemical structures were elucidated on the basis of physicochemical properties and spectral data. RESULT: Fourteen compounds were isolated and identified as 6-hydroxy-stigmasta-4-en-3-one(1), 6-hydroxy-stigmasta4,22-dien-3-one(2), stigmasta-5-en-3-ol-7-one(3), stigmasta-5, 22-dien-3-ol-7-one(4), stigmast-5-en-3, 7-diol(5), stigmast-5, 22-dien-3, 7-diol(6), stigmast-4, 22-dien-3, 6-dione(7), stigmasta-4, 22-dien-3-one(8), ergosta-7, 22-dien-3-ol(9), cycloart-25-en-3,24-diol(10), lupeol(11), aurantiamide acetate (12), stigmasterol(13), hexadecanoic acid (14). CONCLUSION: Compounds 1-12 are obtained from the genus Abelmoschus plant for the first time and also from the Malvaceae for the first time.
Authors: Omnia Hesham Abdelhafez; Michael Atef Fawzy; John Refaat Fahim; Samar Yehia Desoukey; Markus Krischke; Martin J Mueller; Usama Ramadan Abdelmohsen Journal: PLoS One Date: 2018-08-23 Impact factor: 3.240