| Literature DB >> 21757150 |
Rodjawan Supakul1, Suthat Liangpunsakul.
Abstract
The mechanisms underlying alcohol-induced hepatic steatosis are complex, involving the disturbance of several signaling pathways. We have gained a better understanding of the role of the innate immune system in the liver and its effects on lipid metabolism and uncovered a number of circulating factors that can influence the response of the liver to ethanol. In this report, we will focus on the potential role of ceramide on AMP-activated protein kinase, as a mediator of alcohol-induced hepatic steatosis.Entities:
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Year: 2011 PMID： 21757150 PMCID： PMC3137800 DOI： 10.1016/j.trsl.2011.03.005
Source DB: PubMed Journal: Transl Res ISSN： 1878-1810 Impact factor: 7.012