Yizhe Yan1, Kun Xu, Yang Fang, Zhiyong Wang. 1. Hefei National Laboratory for Physical Sciences at Microscale, Department of Chemistry, University of Science and Technology of China, Hefei, 230026, P. R. China.
Abstract
A highly efficient synthesis of trans-alkenylazaarene under catalyst-free conditions was developed via the addition of methylazaarenes to N-sulfonyl aldimines and a subsequent C-N elimination in situ. A one-pot procedure for this addition-elimination was also developed. The reaction could tolerate a broad substrate scope and give the corresponding alkenylazaarenes in high yields.
A highly efficient synthesis of trans-alkenylazaarene under catalyst-free conditions was developed via the addition of n class="Chemical">methylazaarenes to N-sulfonyl aldimines and a subsequent C-N elimination in situ. A one-pot procedure for this addition-elimination was also developed. The reaction could tolerate a broad substrate scope and give the corresponding alkenylazaarenes in high yields.
Authors: Xuyi Yue; Dhruva D Dhavale; Junfeng Li; Zonghua Luo; Jialu Liu; Hao Yang; Robert H Mach; Paul T Kotzbauer; Zhude Tu Journal: Bioorg Med Chem Lett Date: 2018-02-16 Impact factor: 2.823
Authors: Dayana Orozco; Vladimir V Kouznetsov; Armando Bermúdez; Leonor Y Vargas Méndez; Arturo René Mendoza Salgado; Carlos Mario Meléndez Gómez Journal: RSC Adv Date: 2020-01-29 Impact factor: 4.036