Literature DB >> 21755588

Urgent radiotherapy is effective in the treatment of metastatic medulloblastoma causing symptomatic brainstem edema.

Ronald H Shapiro1, Andrew L Chang.   

Abstract

A 3-year-old male who presented with hydrocephalus symptoms was found to have metastatic medulloblastoma with diffuse spinal disease. Thirteen days following surgical resection of his primary tumor, he clinically deteriorated due to worsening brainstem edema. Following intubation, stress-dose steroids, and mannitol, urgent radiotherapy was initiated to the whole brain and cervical cord. The patient improved clinically with a repeat MRI showing decreased leptomeningeal enhancement in the radiation fields. In the literature, there are no reports of successful urgent radiotherapy in medulloblastoma, but in this instance, it proved to be a viable option.
Copyright © 2011 Wiley-Liss, Inc.

Entities:  

Mesh:

Year:  2011        PMID: 21755588     DOI: 10.1002/pbc.23085

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN: 1545-5009            Impact factor:   3.167


  2 in total

1.  An adult multifocal medulloblastoma with diffuse acute postoperative cerebellar swelling: immunohistochemical and molecular genetics analysis.

Authors:  Vladimir Balik; Radek Trojanec; Milena Holzerova; Lucie Tuckova; Igor Sulla; Magdalena Megova; Miroslav Vaverka; Lumir Hrabalek; Jiri Ehrmann
Journal:  Neurosurg Rev       Date:  2014-06-10       Impact factor: 3.042

Review 2.  Delayed diffuse cerebellar swelling after resection of medulloblastoma: case report and review of literature.

Authors:  Ashley L B Raghu; Jothy Kandasamy; Mark Brougham; Pasquale Gallo; Drahus Sokol; Mark A Hughes
Journal:  Childs Nerv Syst       Date:  2017-06-29       Impact factor: 1.475

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.