| Literature DB >> 21755075 |
Zhenyu Lin1, Weiqiang Yang, Guiyun Zhang, Qida Liu, Bin Qiu, Zongwei Cai, Guonan Chen.
Abstract
A novel catalytic colorimetric assay assisted by nicking endonuclease signal amplification (NESA) was developed. With the signal amplification, the detection limit of the p53 target gene can be as low as 1 pM, which is nearly 5 orders of magnitude lower than that of other previously reported colorimetric DNA detection strategies based on catalytic DNAzyme.Entities:
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Year: 2011 PMID： 21755075 DOI： 10.1039/c1cc13146j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222