| Literature DB >> 21751776 |
Xiaotao Zhuo1, Kai Xiang, Fu-Min Zhang, Yong-Qiang Tu.
Abstract
An efficient strategy for the total synthesis of (+)-przewalskin B is reported. The key steps feature an intermolecular S(N)2' substitution of iodoallylic phosphate with organocupper reagent, a diastereoselective organocatalytic aldol cyclization, as well as a Rh(2)(OAc)(4)-mediated intramolecular carbene insertion to the tertiary C-H bond.Entities:
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Year: 2011 PMID： 21751776 DOI： 10.1021/jo201111w
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354