Literature DB >> 21749878

Potentially serious drug-drug interactions among community-dwelling older adult dental patients.

Daniel D Skaar1, Heidi O'Connor.   

Abstract

OBJECTIVES: Reducing adverse drug events, including those resulting from drug-drug interactions, will be a health safety issue of increasing importance for dental practitioners in the coming decades as greater numbers of older adults seek oral health care. The purpose of this study was to identify prescription drugs with the potential for serious interactions and estimate prevalent use among older adults visiting the dentist. STUDY
DESIGN: The Medicare Current Beneficiary Survey is an ongoing series of nationally representative surveys of Medicare beneficiaries. Potentially serious drug interactions were selected with the use of published work by Partnership to Prevent Drug-Drug Interactions. Drug interactions were identified and prevalence estimates made for community-dwelling older adults visiting the dentist. Analyses were completed to test associations between sociodemographic and health-related variables and the use of prescription drugs with the potential for serious interactions.
RESULTS: Overall, 3.4% of those visiting the dentist were estimated to have been prescribed drugs with the potential for a serious drug interaction. Drugs commonly prescribed in dentistry with the potential for serious interactions include the benzodiazepines, macrolide antibiotics, and nonsteroidal antiinflammatory analgesics.
CONCLUSIONS: Understanding potentially harmful drug combinations, their clinical consequences, and the frequency with which implicated drugs are being prescribed will assist practitioners in clinically managing patients and avoiding inappropriate prescribing.
Copyright © 2011 Mosby, Inc. All rights reserved.

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Year:  2011        PMID: 21749878     DOI: 10.1016/j.tripleo.2011.03.048

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod        ISSN: 1079-2104


  3 in total

1.  Frequency and characterization of potential drug interactions in dentistry-a cross-sectional study.

Authors:  Marcelo Lehnen Rodrigues de Oliveira; Gabriela Oltramari Nery; Thalía Tessaro Torresan; Rafaela Alves Arcanjo; Maria Beatriz Cardoso Ferreira; Francisco Montagner
Journal:  Clin Oral Investig       Date:  2022-08-05       Impact factor: 3.606

Review 2.  Immunomodulatory drugs: oral and systemic adverse effects.

Authors:  Antonio Bascones-Martinez; Riikka Mattila; Rafael Gomez-Font; Jukka H Meurman
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2014-01-01

Review 3.  Drug-drug interactions and adverse drug reactions in polypharmacy among older adults: an integrative review.

Authors:  Maria Cristina Soares Rodrigues; Cesar de Oliveira
Journal:  Rev Lat Am Enfermagem       Date:  2016-09-01
  3 in total

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