Literature DB >> 21747663

Cardiac contractility modulation in patients with heart failure refractory to drug treatment.

Philipp Radlberger1, Christopher Adlbrecht, Tarquin Mittermayr.   

Abstract

Cardiac contractility modulation in patients with heart failure refractory to drug treatment aims to strengthen myocardial activity through transmission of nonexcitatory impulses to the heart. The present study reviewed a total of 251 patients from four studies; the results, however, showed a low level of evidence. Crossover analysis showed a strong placebo effect for patients with implants that were switched on after three months. The technology is still in the development stage and further studies are needed.

Entities:  

Keywords:  Cardiac contractility modulation; Cardiac insufficiency; Evidence-based medicine; Health technology assessment; Reimbursement

Year:  2011        PMID: 21747663      PMCID: PMC3126682     

Source DB:  PubMed          Journal:  Exp Clin Cardiol        ISSN: 1205-6626


  16 in total

1.  Cardiac resynchronization in chronic heart failure.

Authors:  William T Abraham; Westby G Fisher; Andrew L Smith; David B Delurgio; Angel R Leon; Evan Loh; Dusan Z Kocovic; Milton Packer; Alfredo L Clavell; David L Hayes; Myrvin Ellestad; Robin J Trupp; Jackie Underwood; Faith Pickering; Cindy Truex; Peggy McAtee; John Messenger
Journal:  N Engl J Med       Date:  2002-06-13       Impact factor: 91.245

2.  Cardiac contractility modulation: A new technologically advanced placebo?

Authors:  Sunil K Sinha; Hugh G Calkins
Journal:  Heart Rhythm       Date:  2006-07-20       Impact factor: 6.343

3.  Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay.

Authors:  S Cazeau; C Leclercq; T Lavergne; S Walker; C Varma; C Linde; S Garrigue; L Kappenberger; G A Haywood; M Santini; C Bailleul; J C Daubert
Journal:  N Engl J Med       Date:  2001-03-22       Impact factor: 91.245

4.  Identifying opportunities to address the congestive heart failure burden: the Improving Cardiovascular Outcomes in Nova Scotia (ICONS) study.

Authors:  Jonathan G Howlett; David E Johnstone; Ingrid Sketris; Michael O'Reilly; Gabrielle S Horne; Jafna L Cox
Journal:  Can J Cardiol       Date:  2003-03-31       Impact factor: 5.223

5.  Synergistic efficacy of enalapril and losartan on exercise performance and oxygen consumption at peak exercise in congestive heart failure.

Authors:  M Guazzi; P Palermo; G Pontone; F Susini; P Agostoni
Journal:  Am J Cardiol       Date:  1999-11-01       Impact factor: 2.778

6.  Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial.

Authors:  Piotr Ponikowski; Stefan D Anker; Joanna Szachniewicz; Darlington Okonko; Mark Ledwidge; Robert Zymlinski; Enda Ryan; Scott M Wasserman; Nigel Baker; Dylan Rosser; Stuart D Rosen; Philip A Poole-Wilson; Waldemar Banasiak; Andrew J S Coats; Ken McDonald
Journal:  J Am Coll Cardiol       Date:  2007-02-05       Impact factor: 24.094

Review 7.  Anaesthesia and cardiac contractility modulation.

Authors:  G Huschak; H Schmidt-Runke; H Rüffert
Journal:  Eur J Anaesthesiol       Date:  2007-06-20       Impact factor: 4.330

8.  Randomized, double blind study of non-excitatory, cardiac contractility modulation electrical impulses for symptomatic heart failure.

Authors:  Martin M Borggrefe; Thomas Lawo; Christian Butter; Herwig Schmidinger; Maurizio Lunati; Burkert Pieske; Anand Ramdat Misier; Antonio Curnis; Dirk Böcker; Andrew Remppis; Joseph Kautzner; Markus Stühlinger; Christophe Leclerq; Milos Táborsky; Maria Frigerio; Michael Parides; Daniel Burkhoff; Gerhard Hindricks
Journal:  Eur Heart J       Date:  2008-02-12       Impact factor: 29.983

9.  A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation in patients with systolic heart failure: rationale, design, and baseline patient characteristics.

Authors:  William T Abraham; Daniel Burkhoff; Koonlawee Nademanee; Peter Carson; Robert Bourge; Kenneth A Ellenbogen; Michael Parides; Alan Kadish
Journal:  Am Heart J       Date:  2008-10       Impact factor: 4.749

10.  Chronic mechanical circulatory support for inotrope-dependent heart failure patients who are not transplant candidates: results of the INTrEPID Trial.

Authors:  Joseph G Rogers; Javed Butler; Steven L Lansman; Alan Gass; Peer M Portner; Michael K Pasque; Richard N Pierson
Journal:  J Am Coll Cardiol       Date:  2007-08-06       Impact factor: 24.094

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  2 in total

Review 1.  An updated review of cardiac devices in heart failure.

Authors:  C Murphy; H Zafar; F Sharif
Journal:  Ir J Med Sci       Date:  2017-03-25       Impact factor: 1.568

2.  Cardiac contractility modulation attenuates structural and electrical remodeling in a chronic heart failure rabbit model.

Authors:  Bin Ning; Feifei Zhang; Xuelian Song; Qingqing Hao; Yingxiao Li; Rong Li; Yi Dang
Journal:  J Int Med Res       Date:  2020-10       Impact factor: 1.671

  2 in total

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