Literature DB >> 21747391

Leishmaniasis: complexity at the host-pathogen interface.

Paul Kaye1, Phillip Scott.   

Abstract

Leishmania is a genus of protozoan parasites that are transmitted by the bite of phlebotomine sandflies and give rise to a range of diseases (collectively known as leishmaniases) that affect over 150 million people worldwide. Cellular immune mechanisms have a major role in the control of infections with all Leishmania spp. However, as discussed in this Review, recent evidence suggests that each host-pathogen combination evokes different solutions to the problems of parasite establishment, survival and persistence. Understanding the extent of this diversity will be increasingly important in ensuring the development of broadly applicable vaccines, drugs and immunotherapeutic interventions.

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Year:  2011        PMID： 21747391     DOI： 10.1038/nrmicro2608

Source DB:  PubMed          Journal:  Nat Rev Microbiol        ISSN： 1740-1526            Impact factor:   60.633


  118 in total

1.  Macrophage tolerance: CD47-SIRP-alpha-mediated signals matter.

Authors:  Hitoshi Takizawa; Markus G Manz
Journal:  Nat Immunol       Date:  2007-12       Impact factor: 25.606

2.  CD40-modulated dual-specificity phosphatases MAPK phosphatase (MKP)-1 and MKP-3 reciprocally regulate Leishmania major infection.

Authors:  Neetu Srivastava; Raki Sudan; Bhaskar Saha
Journal:  J Immunol       Date:  2011-04-06       Impact factor: 5.422

3.  CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major.

Authors:  Yasmine Belkaid; Esther Von Stebut; Susana Mendez; Rosalia Lira; Elisabet Caler; Sylvie Bertholet; Mark C Udey; David Sacks
Journal:  J Immunol       Date:  2002-04-15       Impact factor: 5.422

4.  IL-7 receptor expression provides the potential for long-term survival of both CD62Lhigh central memory T cells and Th1 effector cells during Leishmania major infection.

Authors:  Sara L Colpitts; Nicole M Dalton; Phillip Scott
Journal:  J Immunol       Date:  2009-05-01       Impact factor: 5.422

5.  In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies.

Authors:  Nathan C Peters; Jackson G Egen; Nagila Secundino; Alain Debrabant; Nicola Kimblin; Shaden Kamhawi; Phillip Lawyer; Michael P Fay; Ronald N Germain; David Sacks
Journal:  Science       Date:  2008-08-15       Impact factor: 47.728

6.  Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells.

Authors:  Simona Stäger; Asher Maroof; Soombul Zubairi; Stephanie L Sanos; Manfred Kopf; Paul M Kaye
Journal:  Eur J Immunol       Date:  2006-07       Impact factor: 5.532

7.  The stage-regulated HASPB and SHERP proteins are essential for differentiation of the protozoan parasite Leishmania major in its sand fly vector, Phlebotomus papatasi.

Authors:  Jovana Sádlová; Helen P Price; Barbara A Smith; Jan Votýpka; Petr Volf; Deborah F Smith
Journal:  Cell Microbiol       Date:  2010-12       Impact factor: 3.715

8.  Infectivity of Leishmania mexicana is associated with differential expression of protein kinase C-like triggered during a cell-cell contact.

Authors:  Nidia Alvarez-Rueda; Marlène Biron; Patrice Le Pape
Journal:  PLoS One       Date:  2009-10-23       Impact factor: 3.240

9.  B7-H1 blockade increases survival of dysfunctional CD8(+) T cells and confers protection against Leishmania donovani infections.

Authors:  Trupti Joshi; Susana Rodriguez; Vladimir Perovic; Ian A Cockburn; Simona Stäger
Journal:  PLoS Pathog       Date:  2009-05-15       Impact factor: 6.823

10.  CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis.

Authors:  Charles F Anderson; Mohammed Oukka; Vijay J Kuchroo; David Sacks
Journal:  J Exp Med       Date:  2007-02-05       Impact factor: 14.307
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  323 in total

1.  [Mucocutaneous leishmaniasis and an undesired passenger].

Authors:  Catherine Ronet; Stephen M Beverley; Nicolas Fasel
Journal:  Med Sci (Paris)       Date:  2011-11-30       Impact factor: 0.818

2.  Characterization of regulatory T cell (Treg) function in patients infected with Leishmania braziliensis.

Authors:  Diego L Costa; Luiz H Guimarães; Thiago M Cardoso; Adriano Queiroz; Ednaldo Lago; Ana M Roselino; Olívia Bacellar; Edgar M Carvalho; João S Silva
Journal:  Hum Immunol       Date:  2013-08-28       Impact factor: 2.850

3.  Leishmanicidal effects of amphotericin B in combination with selenium loaded on niosome against Leishmania tropica.

Authors:  Mahshid Mostafavi; Saeedeh Farajzadeh; Iraj Sharifi; Payam Khazaeli; Hamid Sharifi
Journal:  J Parasit Dis       Date:  2019-01-01

4.  Deletion of ubiquitin fold modifier protein Ufm1 processing peptidase Ufsp in L. donovani abolishes Ufm1 processing and alters pathogenesis.

Authors:  Sreenivas Gannavaram; Sonya Davey; Ines Lakhal-Naouar; Robert Duncan; Hira L Nakhasi
Journal:  PLoS Negl Trop Dis       Date:  2014-02-20

5.  Recovery of antigen-specific T cell responses from dogs infected with Leishmania (L.) infantum by use of vaccine associated TLR-agonist adjuvant.

Authors:  Robert G Schaut; Tara L Grinnage-Pulley; Kevin J Esch; Angela J Toepp; Malcolm S Duthie; Randall F Howard; Steven G Reed; Christine A Petersen
Journal:  Vaccine       Date:  2016-09-21       Impact factor: 3.641

Review 6.  Pro- and anti-inflammatory cytokines in cutaneous leishmaniasis: a review.

Authors:  Nahid Maspi; Amir Abdoli; Fathemeh Ghaffarifar
Journal:  Pathog Glob Health       Date:  2016-09-23       Impact factor: 2.894

7.  Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis.

Authors:  Matteo Rossi; Patrik Castiglioni; Mary-Anne Hartley; Remzi Onur Eren; Florence Prével; Chantal Desponds; Daniel T Utzschneider; Dietmar Zehn; Maria G Cusi; F Matthew Kuhlmann; Stephen M Beverley; Catherine Ronet; Nicolas Fasel
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-24       Impact factor: 11.205

8.  Amphotericin B-loaded nanoparticles for local treatment of cutaneous leishmaniasis.

Authors:  Aiman Abu Ammar; Abed Nasereddin; Suheir Ereqat; Mary Dan-Goor; Charles L Jaffe; Eyal Zussman; Ziad Abdeen
Journal:  Drug Deliv Transl Res       Date:  2019-02       Impact factor: 4.617

9.  Immunologic Markers of Protection in Leishmania (Viannia) braziliensis Infection: A 5-Year Cohort Study.

Authors:  Aline C Muniz; Olívia Bacellar; Ednaldo Lima Lago; Augusto M Carvalho; Pedro Paulo Carneiro; Luiz Henrique Guimarães; Paulo N Rocha; Lucas P Carvalho; Marshall Glesby; Edgar M Carvalho
Journal:  J Infect Dis       Date:  2016-05-18       Impact factor: 5.226

10.  Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani.

Authors:  Sayan Chowdhury; Tulika Mukherjee; Somenath Roy Chowdhury; Souvik Sengupta; Sibabrata Mukhopadhyay; Parasuraman Jaisankar; Hemanta K Majumder
Journal:  Antimicrob Agents Chemother       Date:  2014-01-27       Impact factor: 5.191
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