Literature DB >> 21747363

New Merck and Vertex drugs raise standard of care in hepatitis C.

Cormac Sheridan.   

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Year:  2011        PMID： 21747363     DOI： 10.1038/nbt0711-553

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  18 in total

1.  Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.

Authors:  Daniel B Nichols; Guy Fournet; K R Gurukumar; Amartya Basu; Jin-Ching Lee; Naoya Sakamoto; Frank Kozielski; Ira Musmuca; Benoît Joseph; Rino Ragno; Neerja Kaushik-Basu
Journal:  Eur J Med Chem       Date:  2012-01-12       Impact factor: 6.514

2.  Synthesis and evaluation of novel potent HCV NS5A inhibitors.

Authors:  Hongwang Zhang; Longhu Zhou; Franck Amblard; Junxing Shi; Drew R Bobeck; Sijia Tao; Tamara R McBrayer; Phillip M Tharnish; Tony Whitaker; Steven J Coats; Raymond F Schinazi
Journal:  Bioorg Med Chem Lett       Date:  2012-05-24       Impact factor: 2.823

3.  Discovery of SCH 900188: A Potent Hepatitis C Virus NS5B Polymerase Inhibitor Prodrug As a Development Candidate.

Authors:  Kevin X Chen; Srikanth Venkatraman; Gopinadhan N Anilkumar; Qingbei Zeng; Charles A Lesburg; Bancha Vibulbhan; Francisco Velazquez; Tin-Yau Chan; Frank Bennet; Yueheng Jiang; Patrick Pinto; Yuhua Huang; Oleg Selyutin; Sony Agrawal; Hsueh-Cheng Huang; Cheng Li; Kuo-Chi Cheng; Neng-Yang Shih; Joseph A Kozlowski; Stuart B Rosenblum; F George Njoroge
Journal:  ACS Med Chem Lett       Date:  2013-08-12       Impact factor: 4.345

4.  Potent Hepatitis C Virus NS5A Inhibitors Containing a Benzidine Core.

Authors:  Il Hak Bae; Jin Kyu Choi; Chieyeon Chough; Sun Ju Keum; Heesun Kim; Sung Key Jang; B Moon Kim
Journal:  ACS Med Chem Lett       Date:  2013-12-04       Impact factor: 4.345

5.  Structure-activity relationship studies on quinoxalin-2(1H)-one derivatives containing thiazol-2-amine against hepatitis C virus leading to the discovery of BH6870.

Authors:  Qi-Fei Zhong; Rui Liu; Gang Liu
Journal:  Mol Divers       Date:  2015-07-24       Impact factor: 2.943

6.  Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors.

Authors:  Lavanya Bondada; Ramu Rondla; Ugo Pradere; Peng Liu; Chengwei Li; Drew Bobeck; Tamara McBrayer; Philip Tharnish; Jerome Courcambeck; Philippe Halfon; Tony Whitaker; Franck Amblard; Steven J Coats; Raymond F Schinazi
Journal:  Bioorg Med Chem Lett       Date:  2013-09-30       Impact factor: 2.823

Review 7.  Chutes and ladders in hepatitis C nucleoside drug development.

Authors:  Steven J Coats; Ethel C Garnier-Amblard; Franck Amblard; Maryam Ehteshami; Sheida Amiralaei; Hongwang Zhang; Longhu Zhou; Sebastien R L Boucle; Xiao Lu; Lavanya Bondada; Jadd R Shelton; Hao Li; Peng Liu; Chengwei Li; Jong Hyun Cho; Satish N Chavre; Shaoman Zhou; Judy Mathew; Raymond F Schinazi
Journal:  Antiviral Res       Date:  2013-11-23       Impact factor: 5.970

8.  2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase.

Authors:  Ilkay Küçükgüzel; Gökhan Satılmış; K R Gurukumar; Amartya Basu; Esra Tatar; Daniel B Nichols; Tanaji T Talele; Neerja Kaushik-Basu
Journal:  Eur J Med Chem       Date:  2013-09-12       Impact factor: 6.514

9.  Design and synthesis of L- and D-phenylalanine derived rhodanines with novel C5-arylidenes as inhibitors of HCV NS5B polymerase.

Authors:  Bhargav A Patel; Ramalingam Krishnan; Nikhil Khadtare; K R Gurukumar; Amartya Basu; Payal Arora; Aaditya Bhatt; Maulik R Patel; Dibyendu Dana; Sanjai Kumar; Neerja Kaushik-Basu; Tanaji T Talele
Journal:  Bioorg Med Chem       Date:  2013-03-31       Impact factor: 3.641

10.  Discovery of new scaffolds for rational design of HCV NS5B polymerase inhibitors.

Authors:  Andriy G Golub; K R Gurukumar; Amartya Basu; Volodymyr G Bdzhola; Yaroslav Bilokin; Sergiy M Yarmoluk; Jin-Ching Lee; Tanaji T Talele; Daniel B Nichols; Neerja Kaushik-Basu
Journal:  Eur J Med Chem       Date:  2012-09-17       Impact factor: 6.514
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