Literature DB >> 21746955

Sertaconazole nitrate shows fungicidal and fungistatic activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, causative agents of tinea pedis.

Alfonso J Carrillo-Muñoz1, Cristina Tur-Tur, Delia C Cárdenes, Dolors Estivill, Gustavo Giusiano.   

Abstract

The fungistatic and fungicidal activities of sertaconazole against dermatophytes were evaluated by testing 150 clinical isolates of causative agents of tinea pedis, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. The overall geometric means for fungistatic and fungicidal activities of sertaconazole against these isolates were 0.26 and 2.26 μg/ml, respectively, although values were higher for T. mentagrophytes than for the others. This is the first comprehensive demonstration of the fungicidal activity of sertaconazole against dermatophytes.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21746955      PMCID： PMC3165331          DOI： 10.1128/AAC.00219-11

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

1.  Comparative study of the in vitro antifungal activity of bifonazole, naftifine and sertaconazole against yeasts.

Authors:  A J Carrillo-Muñoz; C Tur-Tur; F J Bornay-Llinares; P Arévalo
Journal:  J Chemother       Date:  1999-06       Impact factor: 1.714

2.  In vitro activity of sertaconazole, fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole against pathogenic vaginal yeast isolates.

Authors:  C Palacín; C Tarragó; J Agut; A Guglietta
Journal:  Methods Find Exp Clin Pharmacol       Date:  2001-03

3.  In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.

Authors:  A J Carrillo-Muñoz; A Guglietta; C Palacín; J Casals; O del Valle; C Guardià; V Rodríguez; G Quindós
Journal:  Chemotherapy       Date:  2004-12-08       Impact factor: 2.544

4.  In vitro activity of sertaconazole.

Authors:  C Palacín; A Sacristán; J A Ortiz
Journal:  Arzneimittelforschung       Date:  1992-05

5.  Comparative study of antifungal activity of sertaconazole, terbinafine, and bifonazole against clinical isolates of Candida spp., Cryptococcus neoformans and dermatophytes.

Authors:  A J Carillo-Muñoz; C Tur-Tur
Journal:  Chemotherapy       Date:  1997 Nov-Dec       Impact factor: 2.544

6.  The safety and efficacy of sertaconazole nitrate cream 2% for tinea pedis.

Authors:  Ronald Savin; Joseph Jorizzo
Journal:  Cutis       Date:  2006-10

7.  Sertaconazole: in-vitro antifungal activity against vaginal and other superficial yeast isolates.

Authors:  A J Carrillo-Muñoz; S Brió; G Quindós; C Palacín; A Guglietta; A Espinel-Ingroff
Journal:  J Chemother       Date:  2001-10       Impact factor: 1.714

8.  Cutaneous fungal infections in the United States: Analysis of the National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS), 1995-2004.

Authors:  Anil A Panackal; Elkan F Halpern; Alice J Watson
Journal:  Int J Dermatol       Date:  2009-07       Impact factor: 2.736

9.  In vitro antifungal activity of sertaconazole against 309 dermatophyte clinical isolates.

Authors:  A J Carrillo-Muñoz; B Fernandez-Torres; J Guarro
Journal:  J Chemother       Date:  2003-12       Impact factor: 1.714

10.  In-vitro antifungal activity of sertaconazole, econazole, and bifonazole against Candida spp.

Authors:  A J Carrillo-Muñoz; J M Torres-Rodriguez
Journal:  J Antimicrob Chemother       Date:  1995-10       Impact factor: 5.790
View more
  3 in total

1.  Efficacy of antifungal agents against fungal spores: An in vitro study using microplate laser nephelometry and an artificially infected 3D skin model.

Authors:  Sarah Fink; Anke Burmester; Uta-Christina Hipler; Claudia Neumeister; Marcus R Götz; Cornelia Wiegand
Journal:  Microbiologyopen       Date:  2022-02       Impact factor: 3.139

2.  A comparative randomized open label study to evaluate efficacy, safety and cost effectiveness between topical 2% sertaconazole and topical 1% butenafine in tinea infections of skin.

Authors:  Saket J Thaker; Dimple S Mehta; Hiral A Shah; Jayendra N Dave; Shailesh G Mundhava
Journal:  Indian J Dermatol       Date:  2013-11       Impact factor: 1.494

3.  Hydrocortisone 1% cream and sertaconazole 2% cream to treat facial seborrheic dermatitis: A double-blind, randomized clinical trial.

Authors:  K Balighi; S Z Ghodsi; M Daneshpazhooh; S Ghale-Baghi; M Nasimi; A Azizpour
Journal:  Int J Womens Dermatol       Date:  2016-12-23
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.