| Literature DB >> 2174595 |
M Agterberg1, H Adriaanse, S Barteling, K van Maanen, J Tommassen.
Abstract
A hybrid protein was constructed containing two antigenic determinants of the structural protein VP1 of foot-and-mouth disease virus, inserted in a cell surface-exposed region of Escherichia coli outer membrane protein PhoE. Immunization of guinea-pigs with partially purified protein resulted in high levels of neutralizing antibodies and complete protection against challenge with the virus.Entities:
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Year: 1990 PMID： 2174595 DOI： 10.1016/0264-410x(90)90242-e
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641