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Literature DB >> 21744790

Antibacterial polyketides from the jellyfish-derived fungus Paecilomyces variotii.

Juan Liu¹, Famei Li, Eun La Kim, Jian Lin Li, Jongki Hong, Kyung Sook Bae, Hae Young Chung, Hyung Sik Kim, Jee H Jung.

Abstract

Four new polyketides (1-4) were isolated from the fungus Paecilomyces variotii, which was derived from the jellyfish Nemopilema nomurai. The planar structures and relative configurations of these polyketides were elucidated on the basis of spectroscopic analyses, including 2D NMR experiments. The compounds showed inhibitory activity against pathogenic bacteria including methicillin-resistant Staphylococcus aureus 3089 and multi-drug-resistant Vibrio parahemolyticus 7001 with MIC values in the range 5-40 μg/mL.

Entities: Chemical Species

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Year: 2011 PMID： 21744790 DOI： 10.1021/np200350b

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

11 in total

Review 1. Recent advancements in synthetic methodologies of 3-substituted phthalides and their application in the total synthesis of biologically active natural products.

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Review 2. Metabolites from nematophagous fungi and nematicidal natural products from fungi as an alternative for biological control. Part I: metabolites from nematophagous ascomycetes.

Authors: Thomas Degenkolb; Andreas Vilcinskas
Journal: Appl Microbiol Biotechnol Date: 2015-12-29 Impact factor: 4.813

3. Exploring the Antibacterial and Antifungal Potential of Jellyfish-Associated Marine Fungi by Cultivation-Dependent Approaches.

Authors: Yang Yue; Huahua Yu; Rongfeng Li; Ronge Xing; Song Liu; Pengcheng Li
Journal: PLoS One Date: 2015-12-04 Impact factor: 3.240

4. The In Vitro and In Vivo Anti-Inflammatory Effects of a Phthalimide PPAR-γ Agonist.

Authors: Mingzhi Su; Jiafu Cao; Jin Huang; Sen Liu; Dong Soon Im; Jin-Wook Yoo; Jee H Jung
Journal: Mar Drugs Date: 2017-01-04 Impact factor: 5.118

5. Characterization of Paecilomyces variotii and Talaromyces amestolkiae in Korea Based on the Morphological Characteristics and Multigene Phylogenetic Analyses.

Authors: Thi Thuong Thuong Nguyen; Narayan Chandra Paul; Hyang Burm Lee
Journal: Mycobiology Date: 2016-12-31 Impact factor: 1.858

10. Varioloid A, a new indolyl-6,10b-dihydro-5aH-[1]benzofuro[2,3-b]indole derivative from the marine alga-derived endophytic fungus Paecilomyces variotii EN-291.

Authors: Peng Zhang; Xiao-Ming Li; Xin-Xin Mao; Attila Mándi; Tibor Kurtán; Bin-Gui Wang
Journal: Beilstein J Org Chem Date: 2016-09-09 Impact factor: 2.883

Antibacterial polyketides from the jellyfish-derived fungus Paecilomyces variotii.

Review 1. Recent advancements in synthetic methodologies of 3-substituted phthalides and their application in the total synthesis of biologically active natural products.

Review 2. Metabolites from nematophagous fungi and nematicidal natural products from fungi as an alternative for biological control. Part I: metabolites from nematophagous ascomycetes.

3. Exploring the Antibacterial and Antifungal Potential of Jellyfish-Associated Marine Fungi by Cultivation-Dependent Approaches.

4. The In Vitro and In Vivo Anti-Inflammatory Effects of a Phthalimide PPAR-γ Agonist.

5. Characterization of Paecilomyces variotii and Talaromyces amestolkiae in Korea Based on the Morphological Characteristics and Multigene Phylogenetic Analyses.

Review 6. Jellyfish-Associated Microbiome in the Marine Environment: Exploring Its Biotechnological Potential.

7. Biocontrol Effects of Paecilomyces variotii against Fungal Plant Diseases.

8. Synthesis of PPAR-γ activators inspired by the marine natural product, paecilocin A.

9. Synthesis of Phthalimide Derivatives as Potential PPAR-γ Ligands.

10. Varioloid A, a new indolyl-6,10b-dihydro-5aH-[1]benzofuro[2,3-b]indole derivative from the marine alga-derived endophytic fungus Paecilomyces variotii EN-291.