Literature DB >> 21743685

Cerebral blood flow and metabolism in anxiety and anxiety disorders.

R J Mathew1.   

Abstract

Anxiety disorders are some of the commonest psychiatric disorders and anxiety commonly co-exists with other psychiatric conditions. Anxiety can also be a normal emotion. Thus, study of the neurobiological effects of anxiety is of considerable significance. In the normal brain, cerebral blood flow (CBF) and metabolism (CMR) serve as indices of brain function. CBF/CMR research is expected to provide new insight into alterations in brain function in anxiety disorders and other psychiatric disorders. Possible associations between stress I anxiety I panic and cerebral ischemia I stroke give additional significance to the effects of anxiety on CBF. With the advent of non-invasive techniques, study of CBF/CMR in anxiety disorders became easier. A large numbers of research reports are available on the effects of stress, anxiety and panic on CBF/CMR in normals and anxiety disorder patients. This article reviews the available human research on this topic.

Entities:  

Keywords:  anxiety; anxiety disorders; cerebral blood flow; cerebral metabolism; generalized anxiety disorder; obsessive compulsive disorder; panic disorder; sympathetic stimulation

Year:  1994        PMID: 21743685      PMCID: PMC2972477     

Source DB:  PubMed          Journal:  Indian J Psychiatry        ISSN: 0019-5545            Impact factor:   1.759


  107 in total

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Authors:  W DAMESHEK
Journal:  Blood       Date:  1953-03       Impact factor: 22.113

2.  Hyperventilation-induced cerebral ischemia in panic disorder.

Authors:  R J Mathew
Journal:  Am J Psychiatry       Date:  1993-10       Impact factor: 18.112

3.  Regional cerebral blood flow during rest and skilled hand movements by xenon-133 inhalation and emission computerized tomography.

Authors:  M Lauritzen; L Henriksen; N A Lassen
Journal:  J Cereb Blood Flow Metab       Date:  1981       Impact factor: 6.200

4.  Regional cerebral blood flow during alcohol withdrawal.

Authors:  M Berglund; J Risberg
Journal:  Arch Gen Psychiatry       Date:  1981-03

5.  The relationship between cerebral blood flow and the EEG in normals.

Authors:  D Menon; Z Koles; A Dobbs
Journal:  Can J Neurol Sci       Date:  1980-08       Impact factor: 2.104

6.  Observations on the functional significance of regional cerebral blood flow in "resting" normal subjects.

Authors:  I Prohovnik; K Håkansson; J Risberg
Journal:  Neuropsychologia       Date:  1980       Impact factor: 3.139

7.  Individual differences in cerebral metabolic patterns during pharmacotherapy in obsessive-compulsive disorder: a multiple regression/discriminant analysis of positron emission tomographic data.

Authors:  N P Azari; P Pietrini; B Horwitz; K D Pettigrew; H L Leonard; J L Rapoport; M B Schapiro; S E Swedo
Journal:  Biol Psychiatry       Date:  1993-12-01       Impact factor: 13.382

8.  Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography.

Authors:  S L Rauch; M A Jenike; N M Alpert; L Baer; H C Breiter; C R Savage; A J Fischman
Journal:  Arch Gen Psychiatry       Date:  1994-01

9.  Effects of haloperidol challenge on regional cerebral glucose utilization in normal human subjects.

Authors:  E J Bartlett; J D Brodie; P Simkowitz; S L Dewey; H Rusinek; A P Wolf; J S Fowler; N D Volkow; G Smith; A Wolkin
Journal:  Am J Psychiatry       Date:  1994-05       Impact factor: 18.112

10.  Reduction of cerebrovascular reactivity during hypercapnia.

Authors:  A L López de Pablo; M C González; G Dieguez; B Gómez; S Lluch
Journal:  Am J Physiol       Date:  1982-05
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  3 in total

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Authors:  Suyan Li; Peeyush Kumar T; Sampada Joshee; Timo Kirschstein; Sivan Subburaju; Jahan S Khalili; Jonas Kloepper; Chuang Du; Abdallah Elkhal; Gábor Szabó; Rakesh K Jain; Rüdiger Köhling; Anju Vasudevan
Journal:  Cell Res       Date:  2017-10-31       Impact factor: 25.617

Review 2.  Concussion and the autonomic nervous system: An introduction to the field and the results of a systematic review.

Authors:  Jon L Pertab; Tricia L Merkley; Alex J Cramond; Kelly Cramond; Holly Paxton; Trevor Wu
Journal:  NeuroRehabilitation       Date:  2018       Impact factor: 2.138

3.  Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction.

Authors:  Anass Agrud; Sivan Subburaju; Pranay Goel; Jun Ren; Ashwin Srinivasan Kumar; Barbara J Caldarone; Wangde Dai; Jesus Chavez; Dai Fukumura; Rakesh K Jain; Robert A Kloner; Anju Vasudevan
Journal:  Sci Rep       Date:  2022-03-22       Impact factor: 4.379

  3 in total

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