Literature DB >> 21742222

Biomarkers in acute lung injury--marking forward progress.

Nicolas Barnett1, Lorraine B Ware.   

Abstract

This article reviews the state of the art regarding biomarkers for prediction, diagnosis, and prognosis in acute lung injury. Biomarkers and the goals of biomarker research are defined. Progress along 4 general routes is examined. First, the results of wide-ranging existing protein biomarkers are reported. Second, newer biomarkers awaiting or with strong potential for validation are described. Third, progress in the fields of genomics and proteomics is reported. Finally, given the complexity and number of potential biomarkers, the results of combining clinical predictors with protein and other biomarkers to produce better prognostic and diagnostic indices are examined.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21742222      PMCID： PMC3134784          DOI： 10.1016/j.ccc.2011.04.001

Source DB:  PubMed          Journal:  Crit Care Clin        ISSN： 0749-0704            Impact factor:   3.598


  114 in total

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Authors: 
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Review 5.  Steroids for acute respiratory distress syndrome?

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6.  Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients.

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Review 7.  The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance.

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Review 9.  Current technology in the diagnosis of developmentally related lung disorders.

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