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Literature DB >> 21741594

Beefing up prostate cancer therapy with performance-enhancing (anti-) steroids.

William G Nelson¹, Michael C Haffner, Srinivasan Yegnasubramanian.

Abstract

In the May 26th issue of the New England Journal of Medicine, de Bono et al. report that the inhibition of androgen synthesis by abiraterone acetate prolonged the survival of men with prostate cancer previously treated by androgen suppression.

Entities: Chemical Disease Gene Species

Year: 2011 PMID： 21741594 PMCID： PMC4479125 DOI： 10.1016/j.ccr.2011.06.019

Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743

9 in total

1. Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma.

Authors: Nallasivam Palanisamy; Bushra Ateeq; Shanker Kalyana-Sundaram; Dorothee Pflueger; Kalpana Ramnarayanan; Sunita Shankar; Bo Han; Qi Cao; Xuhong Cao; Khalid Suleman; Chandan Kumar-Sinha; Saravana M Dhanasekaran; Ying-bei Chen; Raquel Esgueva; Samprit Banerjee; Christopher J LaFargue; Javed Siddiqui; Francesca Demichelis; Peter Moeller; Tarek A Bismar; Rainer Kuefer; Douglas R Fullen; Timothy M Johnson; Joel K Greenson; Thomas J Giordano; Patrick Tan; Scott A Tomlins; Sooryanarayana Varambally; Mark A Rubin; Christopher A Maher; Arul M Chinnaiyan
Journal: Nat Med Date: 2010-06-06 Impact factor: 53.440

2. Abiraterone and increased survival in metastatic prostate cancer.

Authors: Johann S de Bono; Christopher J Logothetis; Arturo Molina; Karim Fizazi; Scott North; Luis Chu; Kim N Chi; Robert J Jones; Oscar B Goodman; Fred Saad; John N Staffurth; Paul Mainwaring; Stephen Harland; Thomas W Flaig; Thomas E Hutson; Tina Cheng; Helen Patterson; John D Hainsworth; Charles J Ryan; Cora N Sternberg; Susan L Ellard; Aude Fléchon; Mansoor Saleh; Mark Scholz; Eleni Efstathiou; Andrea Zivi; Diletta Bianchini; Yohann Loriot; Nicole Chieffo; Thian Kheoh; Christopher M Haqq; Howard I Scher
Journal: N Engl J Med Date: 2011-05-26 Impact factor: 91.245

Review 3. Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis.

Authors: Howard I Scher; Charles L Sawyers
Journal: J Clin Oncol Date: 2005-11-10 Impact factor: 44.544

4. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study.

Authors: Howard I Scher; Tomasz M Beer; Celestia S Higano; Aseem Anand; Mary-Ellen Taplin; Eleni Efstathiou; Dana Rathkopf; Julia Shelkey; Evan Y Yu; Joshi Alumkal; David Hung; Mohammad Hirmand; Lynn Seely; Michael J Morris; Daniel C Danila; John Humm; Steve Larson; Martin Fleisher; Charles L Sawyers
Journal: Lancet Date: 2010-04-14 Impact factor: 79.321

5. Adverse effects of androgen deprivation therapy: defining the problem and promoting health among men with prostate cancer.

Authors: Philip J Saylor; Matthew R Smith
Journal: J Natl Compr Canc Netw Date: 2010-02 Impact factor: 11.908

6. Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program.

Authors: Rajal B Shah; Rohit Mehra; Arul M Chinnaiyan; Ronglai Shen; Debashis Ghosh; Ming Zhou; Gary R Macvicar; Soorynarayana Varambally; Jason Harwood; Tarek A Bismar; Robert Kim; Mark A Rubin; Kenneth J Pienta
Journal: Cancer Res Date: 2004-12-15 Impact factor: 12.701

7. Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target?

Authors: Michael C Haffner; Angelo M De Marzo; Alan K Meeker; William G Nelson; Srinivasan Yegnasubramanian
Journal: Clin Cancer Res Date: 2011-03-08 Impact factor: 12.531

8. Phase II trial of docetaxel with rapid androgen cycling for progressive noncastrate prostate cancer.

Authors: Dana Rathkopf; Michael A Carducci; Michael J Morris; Susan F Slovin; Mario A Eisenberger; Roberto Pili; Samuel R Denmeade; Moshe Kelsen; Tracy Curley; Melinda Halter; Connie Collins; Martin Fleisher; Glenn Heller; Sharyn D Baker; Howard I Scher
Journal: J Clin Oncol Date: 2008-06-20 Impact factor: 44.544

Review 9. Recurrent gene fusions in prostate cancer.

Authors: Chandan Kumar-Sinha; Scott A Tomlins; Arul M Chinnaiyan
Journal: Nat Rev Cancer Date: 2008-06-19 Impact factor: 60.716