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Literature DB >> 2174129

Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes.

Abstract

A complementary DNA encoding a voltage-gated chloride channel from Torpedo marmorata electric organ was cloned by expressing hybrid-depleted messenger RNA in Xenopus oocytes. The predicted protein has a sequence of 805 amino acids containing several putative membrane-spanning domains. Expression of the protein in Xenopus oocytes shows that it is sufficient for channel function.

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Year: 1990 PMID： 2174129 DOI： 10.1038/348510a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

135 in total

1. Regulation of a hyperpolarization-activated chloride current in murine respiratory ciliated cells.

Authors: R Tarran; B E Argent; M A Gray
Journal: J Physiol Date: 2000-04-15 Impact factor: 5.182

2. Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.

Authors: J Eggermont; G Buyse; T Voets; J Tytgat; H De Smedt; G Droogmans; B Nilius
Journal: Biochem J Date: 1997-07-01 Impact factor: 3.857

Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes.

1. Regulation of a hyperpolarization-activated chloride current in murine respiratory ciliated cells.

2. Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.

3. The yeast CLC protein counteracts vesicular acidification during iron starvation.

4. Conduction mechanisms of chloride ions in ClC-type channels.

5. Side-chain charge effects and conductance determinants in the pore of ClC-0 chloride channels.

6. Properties of single- and double-barreled Cl channels of shark rectal gland in planar bilayers.

7. Sorting motifs of the endosomal/lysosomal CLC chloride transporters.

8. New nucleotide sequence data on the EMBL File Server.

Review 9. The TMEM16 protein family: a new class of chloride channels?

Review 10. Review. CLC-mediated anion transport in plant cells.