Literature DB >> 21738960

The use of oxybutynin for treating facial hyperhidrosis.

Nelson Wolosker1, José Ribas Milanez de Campos, Paulo Kauffman, Marco Antonio Munia, Samantha Neves, Fábio Biscegli Jatene, Pedro Puech-Leão.   

Abstract

BACKGROUND: Facial hyperhidrosis is a disease that may lead patients to serious emotional disturbances. Video-assisted thoracic sympathectomy provides excellent resolution of facial hyperhidrosis, but is associated with certain complications. The most frequent and important complication is compensatory hyperhidrosis. Especially in patients who have undergone resection of the second thoracic ganglion, the risk of severe compensatory hyperhidrosis is higher, which may cause dissatisfaction with the procedure.
OBJECTIVE: The aim of this study was to evaluate the efficacy of the use of low doses of oxybutynin in treating facial hyperhidrosis as well as the level of patient satisfaction with its use.
METHODS: 25 patients with facial hyperhidrosis were treated with oxybutynin. The patients underwent 2 evaluations: before and after treatment. These evaluations were used to assess the patients' clinical improvement and quality of life.
RESULTS: We observed that more than 75% of the patients evolved with an improvement in facial hyperhidrosis, and 52% of them presented a great improvement.
CONCLUSION: Treatment of facial hyperhidrosis with oxybutynin is a good alternative to sympathectomy, since it presents good results and improves quality of life, in addition to not exposing patients to the risk of experiencing the side effects of sympathectomy.

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Year:  2011        PMID: 21738960     DOI: 10.1590/s0365-05962011000300005

Source DB:  PubMed          Journal:  An Bras Dermatol        ISSN: 0365-0596            Impact factor:   1.896


  8 in total

1.  Long-term results of oxybutynin use in treating facial hyperhidrosis.

Authors:  Nelson Wolosker; Marcelo Passos Teivelis; Mariana Krutman; Taiz Pereira Dozono de Almeida Campbell; Paulo Kauffman; José Ribas de Campos; Pedro Puech-Leão
Journal:  An Bras Dermatol       Date:  2014 Nov-Dec       Impact factor: 1.896

Review 2.  Oxybutynin for the Treatment of Primary Hyperhidrosis: Current State of the Art.

Authors:  Anna Campanati; Stamatis Gregoriou; George Kontochristopoulos; Annamaria Offidani
Journal:  Skin Appendage Disord       Date:  2015-01-30

3.  Long-term results of oxybutynin treatment for palmar hyperhidrosis.

Authors:  Nelson Wolosker; Marcelo Passos Teivelis; Mariana Krutman; Rafael P de Paula; José R M de Campos; Paulo Kauffman; Pedro Puech-Leão
Journal:  Clin Auton Res       Date:  2014-11-27       Impact factor: 4.435

4.  Treatment of uncommon sites of focal primary hyperhidrosis: experience with pharmacological therapy using oxybutynin.

Authors:  Marcelo Passos Teivelis; Nelson Wolosker; Mariana Krutman; Paulo Kauffman; José Ribas Milanez de Campos; Pedro Puech-Leão
Journal:  Clinics (Sao Paulo)       Date:  2014-09       Impact factor: 2.365

Review 5.  Oxybutynin as an alternative treatment for hyperhidrosis.

Authors:  Sergio Delort; Evaldo Marchi; Marcos Antônio Corrêa
Journal:  An Bras Dermatol       Date:  2017 Mar-Apr       Impact factor: 1.896

6.  Compensatory quadrant-hyperhidrosis after contralateral intrathoracic surgery: a case report.

Authors:  Stefan Brodoehl; Otto Wilhelm Witte; Albrecht Guenther
Journal:  J Med Case Rep       Date:  2013-01-18

7.  Evaluation of anxiety and depression prevalence in patients with primary severe hyperhidrosis.

Authors:  Gleide Maria Gatto Bragança; Sonia Oliveira Lima; Aloisio Ferreira Pinto Neto; Lucas Menezes Marques; Enaldo Vieira de Melo; Francisco Prado Reis
Journal:  An Bras Dermatol       Date:  2014 Mar-Apr       Impact factor: 1.896

8.  Analysis of oxybutynin treatment for hyperhidrosis in patients aged over 40 years.

Authors:  Nelson Wolosker; Mariana Krutman; Marcelo Passos Teivelis; Rafael Pessanha de Paula; Paulo Kauffman; Jose Ribas Milanez de Campos; Pedro Puech-Leão
Journal:  Einstein (Sao Paulo)       Date:  2014 Jan-Mar
  8 in total

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