Literature DB >> 21738496

Control of mRNA stability by SAPKs.

Miguel A Rodríguez-Gabriel1, Paul Russell.   

Abstract

Control of mRNA turnover is an essential step in the regulation of gene expression in eukaryotes. The concerted action of many enzymes regulates the way each mRNA is degraded. Moreover, the degradation of each mRNA is influenced by the environment surrounding the cell. The conection between the environment and changes in the half-lifes of mRNAs is regulated by the activity of stress activated MAP kinases (SAPKs) and their substrates. Here we will describe some of those mechanisms, and how SAPKs regulate mRNA stability in eukaryotic cells.

Year:  2008        PMID： 21738496      PMCID： PMC3129863          DOI： 10.1007/4735_2007_0248

Source DB:  PubMed          Journal:  Top Curr Genet        ISSN： 1610-2096


  76 in total

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Journal:  Cell       Date:  2002-02-22       Impact factor: 41.582

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Journal:  J Biol Chem       Date:  2003-07-25       Impact factor: 5.157

5.  Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast.

Authors:  Shinya Takahashi; Yasuhiro Araki; Takeshi Sakuno; Toshiaki Katada
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6.  A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.

Authors:  H Min; C W Turck; J M Nikolic; D L Black
Journal:  Genes Dev       Date:  1997-04-15       Impact factor: 11.361

7.  The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae.

Authors:  M Tucker; M A Valencia-Sanchez; R R Staples; J Chen; C L Denis; R Parker
Journal:  Cell       Date:  2001-02-09       Impact factor: 41.582

8.  The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.

Authors:  Keith M Giles; John M Daly; Dianne J Beveridge; Andrew M Thomson; Dominic C Voon; Henry M Furneaux; Jalal A Jazayeri; Peter J Leedman
Journal:  J Biol Chem       Date:  2002-11-12       Impact factor: 5.157

9.  Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease.

Authors:  Wi S Lai; Elizabeth A Kennington; Perry J Blackshear
Journal:  Mol Cell Biol       Date:  2003-06       Impact factor: 4.272

10.  MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay.

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Journal:  EMBO J       Date:  2004-03-11       Impact factor: 11.598
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  2 in total

1.  Glucocorticoid regulation of human pulmonary surfactant protein-B (SP-B) mRNA stability is independent of activated glucocorticoid receptor.

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Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2011-03-11       Impact factor: 5.464

2.  Post-transcriptional regulation of VEGF-A mRNA levels by mitogen-activated protein kinases (MAPKs) during metabolic stress associated with ischaemia/reperfusion.

Authors:  Bryan W Miller; Joanna M Hay; Sally A Prigent; Martin Dickens
Journal:  Mol Cell Biochem       Date:  2012-05-05       Impact factor: 3.396
  2 in total

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