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Literature DB >> 21738154

The brain splits obesity and hypertension.

Michael H Humphreys.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2011 PMID： 21738154 DOI： 10.1038/nm0711-782

Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440

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14 in total

Review 1. Obesity and inflammation: a new look at an old problem.

Authors: Sachin Mehta; John A Farmer
Journal: Curr Atheroscler Rep Date: 2007-08 Impact factor: 5.113

Review 2. Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond.

Authors: A Christine Könner; Tim Klöckener; Jens C Brüning
Journal: Physiol Behav Date: 2009-04-05

3. Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits.

Authors: Larissa J Prior; Nina Eikelis; James A Armitage; Pamela J Davern; Sandra L Burke; Jean-Pierre Montani; Benjamin Barzel; Geoffrey A Head
Journal: Hypertension Date: 2010-03-01 Impact factor: 10.190

Review 4. Cardiovascular effects of melanocortins.

Authors: Michael H Humphreys; Xi-Ping Ni; David Pearce
Journal: Eur J Pharmacol Date: 2011-01-01 Impact factor: 4.432

5. Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation.

Authors: Shannon M Harlan; Donald A Morgan; Khristofor Agassandian; Deng-Fu Guo; Martin D Cassell; Curt D Sigmund; Allyn L Mark; Kamal Rahmouni
Journal: Circ Res Date: 2011-02-10 Impact factor: 17.367

6. Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia.

Authors: Lakshmi S Tallam; David E Stec; Mary A Willis; Alexandre A da Silva; John E Hall
Journal: Hypertension Date: 2005-07-18 Impact factor: 10.190

7. The relationship between inflammation, obesity and risk for hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA).

Authors: S G Lakoski; M Cushman; D S Siscovick; R S Blumenthal; W Palmas; G Burke; D M Herrington
Journal: J Hum Hypertens Date: 2010-10-14 Impact factor: 3.012

8. NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia.

Authors: Pil-Geum Jang; Cherl Namkoong; Gil Myoung Kang; Man-Wook Hur; Seung-Whan Kim; Geun Hyang Kim; Yeoungsup Kang; Min-Jae Jeon; Eun Hee Kim; Myung-Shik Lee; Michael Karin; Ja-Hyun Baik; Joong-Yeol Park; Ki-Up Lee; Young-Bum Kim; Min-Seon Kim
Journal: J Biol Chem Date: 2010-01-22 Impact factor: 5.157

9. Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse.

Authors: Xi-Ping Ni; David Pearce; Andrew A Butler; Roger D Cone; Michael H Humphreys
Journal: J Clin Invest Date: 2003-04 Impact factor: 14.808

The brain splits obesity and hypertension.

Review 1. Obesity and inflammation: a new look at an old problem.

Review 2. Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond.

3. Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits.

Review 4. Cardiovascular effects of melanocortins.

5. Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation.

6. Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia.

7. The relationship between inflammation, obesity and risk for hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA).

8. NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia.

9. Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse.

10. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.

1. Hypertension in obesity: the role of hypothalamic inflammation.

Review 2. Metabolic syndrome, aging and involvement of oxidative stress.

Review 3. Hypothalamic inflammation: a double-edged sword to nutritional diseases.

Review 4. Inflammatory cause of metabolic syndrome via brain stress and NF-κB.