Literature DB >> 21738147

Antibiotic bill doesn't GAIN enough ground.

Paul G Ambrose1.   

Abstract

With an eye to tackling the growing problem of antimicrobial drug resistance, uS lawmakers last month proposed new incentives to jump-start the ailing antibiotic industry. but the legislation as written is not likely to have the intended consequences, as it fails to adequately shield companies from competition with generic drugs. To truly entice investment and research from the drug industry, the bill needs to simplify the path to regulatory approval, provide greater protection from generic competition and aid drug companies with intellectual property extensions, tax relief and guaranteed market commitments.

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Year:  2011        PMID: 21738147     DOI: 10.1038/nm0711-772

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


  3 in total

Review 1.  Fresh approaches to anti-infective therapies.

Authors:  Carl Nathan
Journal:  Sci Transl Med       Date:  2012-06-27       Impact factor: 17.956

2.  Using four decades of FDA orphan drug designations to describe trends in rare disease drug development: substantial growth seen in development of drugs for rare oncologic, neurologic, and pediatric-onset diseases.

Authors:  Kathleen L Miller; Lewis J Fermaglich; Janet Maynard
Journal:  Orphanet J Rare Dis       Date:  2021-06-09       Impact factor: 4.123

3.  Small molecule deubiquitinase inhibitors promote macrophage anti-infective capacity.

Authors:  Marie-Eve Charbonneau; Marta J Gonzalez-Hernandez; Hollis D Showalter; Nicholas J Donato; Christiane E Wobus; Mary X D O'Riordan
Journal:  PLoS One       Date:  2014-08-05       Impact factor: 3.240

  3 in total

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