Literature DB >> 21735001

Synthesis of a cyclic peptide/protein using the NEXT-A reaction followed by cyclization.

Toshimasa Hamamoto1, Masahiko Sisido, Takashi Ohtsuki, Masumi Taki.   

Abstract

By using the NEXT-A reaction, we introduced a non-natural amino acid at the N-terminus of a peptide/protein that contained a cysteine unit. The side chain of the introduced amino acid spontaneously reacted with the cysteine to afford a cyclic peptide/protein.

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Year:  2011        PMID： 21735001     DOI： 10.1039/c1cc12196k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids.

Authors:  Claudio Zambaldo; Xiaozhou Luo; Angad P Mehta; Peter G Schultz
Journal:  J Am Chem Soc       Date:  2017-08-15       Impact factor: 15.419

2.  Kinetic analysis of the leucyl/phenylalanyl-tRNA-protein transferase with acceptor peptides possessing different N-terminal penultimate residues.

Authors:  Jun Kawaguchi; Kumino Maejima; Hiroyuki Kuroiwa; Masumi Taki
Journal:  FEBS Open Bio       Date:  2013-06-11       Impact factor: 2.693

3.  Bioinspired strategy for the ribosomal synthesis of thioether-bridged macrocyclic peptides in bacteria.

Authors:  Nina Bionda; Abby L Cryan; Rudi Fasan
Journal:  ACS Chem Biol       Date:  2014-08-01       Impact factor: 5.100
  3 in total

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