Literature DB >> 21734805

Is hyperhomocysteinemia relevant in patients with celiac disease?

Giovanni Casella1, Gabrio Bassotti, Vincenzo Villanacci, Camillo Di Bella, Fabio Pagni, Gian Luigi Corti, Giuseppe Sabatino, Mara Piatti, Vittorio Baldini.   

Abstract

AIM: To investigate whether this might be related to the presence of hyperhomocysteinemia.
METHODS: From January 1998 to December 2008, we evaluated the presence of hyperhomocysteinemia in a series of 165 adult celiac disease (CD) patients (138 females and 27 males, mean age 43 years).
RESULTS: Hyperhomocysteinemia was evident in 32 patients (19.3%), although most of them had moderate levels (mean value 25 mcg/ml; range 15-30). Only one patient had a history of myocardial infarction (heterozygosis for N5-N10-metil tetrahydrofolate reductase mutation).
CONCLUSION: The systematic assessment of hyperhomocysteinemia seems, at present, unjustified in CD patients.

Entities:  

Keywords:  Celiac disease; Endoscopy; Histology; Hyperhomocysteinemia

Mesh:

Year:  2011        PMID: 21734805      PMCID: PMC3129508          DOI: 10.3748/wjg.v17.i24.2941

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  27 in total

1.  Latent coeliac disease, hyperhomocysteinemia and pulmonary thromboembolism: a close link?

Authors:  Maurizio Gabrielli; Angelo Santoliquido; Giovanni Gasbarrini; Paolo Pola; Antonio Gasbarrini
Journal:  Thromb Haemost       Date:  2003-01       Impact factor: 5.249

Review 2.  Homocysteine and atherothrombosis.

Authors:  G N Welch; J Loscalzo
Journal:  N Engl J Med       Date:  1998-04-09       Impact factor: 91.245

3.  [Lower extremity deep vein thrombosis associated with gluten-sensitivity celiac disease].

Authors:  E N Baryshnikov; L M Krums; N N Vorob'eva; A I Parfenov
Journal:  Ter Arkh       Date:  2010       Impact factor: 0.467

4.  Reversible hypertension following coeliac disease treatment: the role of moderate hyperhomocysteinaemia and vascular endothelial dysfunction.

Authors:  P O Lim; N Tzemos; C A J Farquharson; J E Anderson; P Deegan; R S MacWalter; A D Struthers; T M MacDonald
Journal:  J Hum Hypertens       Date:  2002-06       Impact factor: 3.012

Review 5.  Total homocysteine and cardiovascular disease.

Authors:  O Nygård; S E Vollset; H Refsum; L Brattström; P M Ueland
Journal:  J Intern Med       Date:  1999-11       Impact factor: 8.989

6.  Hyperhomocysteinemia in chronic alcoholism: correlation with folate, vitamin B-12, and vitamin B-6 status.

Authors:  M L Cravo; L M Glória; J Selhub; M R Nadeau; M E Camilo; M P Resende; J N Cardoso; C N Leitão; F C Mira
Journal:  Am J Clin Nutr       Date:  1996-02       Impact factor: 7.045

7.  Hyperhomocysteinemia and deep-vein thrombosis. A case-control study.

Authors:  P Simioni; P Prandoni; A Burlina; D Tormene; C Sardella; V Ferrari; L Benedetti; A Girolami
Journal:  Thromb Haemost       Date:  1996-12       Impact factor: 5.249

Review 8.  Hyperhomocysteinemia in chronic alcoholism: relations to folic acid and vitamins B(6) and B(12) status.

Authors:  M L Cravo; M E Camilo
Journal:  Nutrition       Date:  2000-04       Impact factor: 4.008

9.  Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.

Authors:  L A Kluijtmans; L P van den Heuvel; G H Boers; P Frosst; E M Stevens; B A van Oost; M den Heijer; F J Trijbels; R Rozen; H J Blom
Journal:  Am J Hum Genet       Date:  1996-01       Impact factor: 11.025

10.  Hyperhomocysteinemia as a risk factor for deep-vein thrombosis.

Authors:  M den Heijer; T Koster; H J Blom; G M Bos; E Briet; P H Reitsma; J P Vandenbroucke; F R Rosendaal
Journal:  N Engl J Med       Date:  1996-03-21       Impact factor: 91.245

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  5 in total

1.  Hyperhomocysteinemia in patients with Crohn's disease.

Authors:  G Casella; E Antonelli; C Di Bella; E Di Marco; M Piatti; V Villanacci; S Bologna; V Baldini; G Bassotti
Journal:  Tech Coloproctol       Date:  2013-03-08       Impact factor: 3.781

2.  The thrombophilic network of autoantibodies in celiac disease.

Authors:  Aaron Lerner; Nancy Agmon-Levin; Yinon Shapira; Boris Gilburd; Sandra Reuter; Idit Lavi; Yehuda Shoenfeld
Journal:  BMC Med       Date:  2013-04-04       Impact factor: 8.775

3.  [An atypical presentation of celiac disease: central retinal vein occlusion].

Authors:  Taieb Jomni; Syrine Bellakhal; Maher Abouda; Imene Abdelaali; Hédi Douggui
Journal:  Pan Afr Med J       Date:  2015-11-25

4.  B vitamins related to homocysteine metabolism in adults celiac disease patients: a cross-sectional study.

Authors:  Flávia Xavier Valente; Tatiana do Nascimento Campos; Luís Fernando de Sousa Moraes; Helen Hermana Miranda Hermsdorff; Leandro de Morais Cardoso; Helena Maria Pinheiro-Sant'Ana; Flávio Augusto Barros Gilberti; Maria do Carmo Gouveia Peluzio
Journal:  Nutr J       Date:  2015-10-20       Impact factor: 3.271

5.  CLASH: Complementary Linkage with Anchoring and Scoring for Heterogeneous biomolecular and clinical data.

Authors:  Yonghyun Nam; Myungjun Kim; Kyungwon Lee; Hyunjung Shin
Journal:  BMC Med Inform Decis Mak       Date:  2016-07-25       Impact factor: 2.796

  5 in total

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