Literature DB >> 21734699

Cancer: when antioxidants are bad.

Rushika M Perera1, Nabeel Bardeesy.   

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Year:  2011        PMID： 21734699     DOI： 10.1038/475043a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  10 in total

Review 1.  Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway.

Authors:  Thomas W Kensler; Nobunao Wakabayashi; Shyam Biswal
Journal:  Annu Rev Pharmacol Toxicol       Date:  2007       Impact factor: 13.820

2.  The antioxidant function of the p53 tumor suppressor.

Authors:  Anna A Sablina; Andrei V Budanov; Galina V Ilyinskaya; Larissa S Agapova; Julia E Kravchenko; Peter M Chumakov
Journal:  Nat Med       Date:  2005-11-13       Impact factor: 53.440

3.  Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts.

Authors:  K Irani; Y Xia; J L Zweier; S J Sollott; C J Der; E R Fearon; M Sundaresan; T Finkel; P J Goldschmidt-Clermont
Journal:  Science       Date:  1997-03-14       Impact factor: 47.728

4.  c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability.

Authors:  Omid Vafa; Mark Wade; Suzanne Kern; Michelle Beeche; Tej K Pandita; Garret M Hampton; Geoffrey M Wahl
Journal:  Mol Cell       Date:  2002-05       Impact factor: 17.970

5.  Pancreatic cancers require autophagy for tumor growth.

Authors:  Shenghong Yang; Xiaoxu Wang; Gianmarco Contino; Marc Liesa; Ergun Sahin; Haoqiang Ying; Alexandra Bause; Yinghua Li; Jayne M Stommel; Giacomo Dell'antonio; Josef Mautner; Giovanni Tonon; Marcia Haigis; Orian S Shirihai; Claudio Doglioni; Nabeel Bardeesy; Alec C Kimmelman
Journal:  Genes Dev       Date:  2011-03-15       Impact factor: 11.361

6.  c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.

Authors:  Ping Gao; Irina Tchernyshyov; Tsung-Cheng Chang; Yun-Sil Lee; Kayoko Kita; Takafumi Ochi; Karen I Zeller; Angelo M De Marzo; Jennifer E Van Eyk; Joshua T Mendell; Chi V Dang
Journal:  Nature       Date:  2009-02-15       Impact factor: 49.962

Review 7.  NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer.

Authors:  John D Hayes; Michael McMahon
Journal:  Trends Biochem Sci       Date:  2009-03-25       Impact factor: 13.807

8.  HIF-dependent antitumorigenic effect of antioxidants in vivo.

Authors:  Ping Gao; Huafeng Zhang; Ramani Dinavahi; Feng Li; Yan Xiang; Venu Raman; Zaver M Bhujwalla; Dean W Felsher; Linzhao Cheng; Jonathan Pevsner; Linda A Lee; Gregg L Semenza; Chi V Dang
Journal:  Cancer Cell       Date:  2007-09       Impact factor: 31.743

Review 9.  Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

Authors:  Dunyaporn Trachootham; Jerome Alexandre; Peng Huang
Journal:  Nat Rev Drug Discov       Date:  2009-05-29       Impact factor: 84.694

10.  Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.

Authors:  Gina M DeNicola; Florian A Karreth; Timothy J Humpton; Aarthi Gopinathan; Cong Wei; Kristopher Frese; Dipti Mangal; Kenneth H Yu; Charles J Yeo; Eric S Calhoun; Francesca Scrimieri; Jordan M Winter; Ralph H Hruban; Christine Iacobuzio-Donahue; Scott E Kern; Ian A Blair; David A Tuveson
Journal:  Nature       Date:  2011-07-06       Impact factor: 49.962
  10 in total
  30 in total

1.  Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.

Authors:  Juliane Hellfritsch; Julian Kirsch; Manuela Schneider; Tamara Fluege; Markus Wortmann; Jeroen Frijhoff; Markus Dagnell; Theres Fey; Irene Esposito; Pirkko Kölle; Kristin Pogoda; José Pedro Friedmann Angeli; Irina Ingold; Peter Kuhlencordt; Arne Östman; Ulrich Pohl; Marcus Conrad; Heike Beck
Journal:  Antioxid Redox Signal       Date:  2015-04-10       Impact factor: 8.401

Review 2.  NRF2 and cancer: the good, the bad and the importance of context.

Authors:  Michael B Sporn; Karen T Liby
Journal:  Nat Rev Cancer       Date:  2012-07-19       Impact factor: 60.716

3.  The study of inducing apoptosis effect of fructose 1,6-bisphosphate on the papillary thyroid carcinoma cell and its related mechanism.

Authors:  Yan Li; Wei Wei; Hu-Wei Shen; Wen-Qing Hu
Journal:  Tumour Biol       Date:  2014-01-12

4.  Pro-oxidant and antioxidant effects of N-acetylcysteine regulate doxorubicin-induced NF-kappa B activity in leukemic cells.

Authors:  Nnenna Adimora Finn; Melissa Lambeth Kemp
Journal:  Mol Biosyst       Date:  2011-12-01

5.  Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.

Authors:  Lijuan Zhan; Hao Zhang; Qiang Zhang; Courtney G Woods; Yanyan Chen; Peng Xue; Jian Dong; Erik J Tokar; Yuanyuan Xu; Yongyong Hou; Jingqi Fu; Kathy Yarborough; Aiping Wang; Weidong Qu; Michael P Waalkes; Melvin E Andersen; Jingbo Pi
Journal:  Free Radic Biol Med       Date:  2012-06-07       Impact factor: 7.376

6.  PFKFB3 regulates oxidative stress homeostasis via its S-glutathionylation in cancer.

Authors:  Minsuh Seo; Yong-Hwan Lee
Journal:  J Mol Biol       Date:  2013-12-01       Impact factor: 5.469

Review 7.  The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene?

Authors:  Phillip Shelton; Anil K Jaiswal
Journal:  FASEB J       Date:  2012-10-29       Impact factor: 5.191

8.  Antitumor effect of fructose 1,6-bisphosphate and its mechanism in hepatocellular carcinoma cells.

Authors:  Yin-Xiang Lu; Xi-Can Yu; Mei-Ying Zhu
Journal:  Tumour Biol       Date:  2013-10-01

9.  KRas, ROS and the initiation of pancreatic cancer.

Authors:  Peter Storz
Journal:  Small GTPases       Date:  2016-05-24

10.  Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.

Authors:  Geou-Yarh Liou; Heike Döppler; Kathleen E DelGiorno; Lizhi Zhang; Michael Leitges; Howard C Crawford; Michael P Murphy; Peter Storz
Journal:  Cell Rep       Date:  2016-03-03       Impact factor: 9.423
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