CONCLUSION: Imaging of the endolymphatic space was possible in most cases after administering a standard dose of gadolinium (Gd) by using heavily T2-weighted 3D fluid-attenuated inversion recovery (hT(2)W-3D-FLAIR) magnetic resonance imaging (MRI). OBJECTIVES: The aim of this study was to characterize the contrast enhancement in the inner ear after intravenous injection of Gd and to compare the signal intensity after a double dose or standard dose of Gd. METHODS: We injected a standard dose of gadodiamide hydrate (DTPA-BMA) or a double dose of gadoteridol (HP-DO3A) intravenously in patients affected by Meniere's disease and performed hT(2)W-3D-FLAIR 3 T MRI. Contrast enhancement of the basal turn of the cochlea was evaluated semiquantitatively. RESULTS: Endolymphatic hydrops was observed in the cochlea and vestibule of the affected ears of patients with Meniere's disease in both the double-dose group and the standard-dose group.
CONCLUSION: Imaging of the endolymphatic space was possible in most cases after administering a standard dose of gadolinium (Gd) by using heavily T2-weighted 3D fluid-attenuated inversion recovery (hT(2)W-3D-FLAIR) magnetic resonance imaging (MRI). OBJECTIVES: The aim of this study was to characterize the contrast enhancement in the inner ear after intravenous injection of Gd and to compare the signal intensity after a double dose or standard dose of Gd. METHODS: We injected a standard dose of gadodiamide hydrate (DTPA-BMA) or a double dose of gadoteridol (HP-DO3A) intravenously in patients affected by Meniere's disease and performed hT(2)W-3D-FLAIR 3 T MRI. Contrast enhancement of the basal turn of the cochlea was evaluated semiquantitatively. RESULTS: Endolymphatic hydrops was observed in the cochlea and vestibule of the affected ears of patients with Meniere's disease in both the double-dose group and the standard-dose group.
Authors: K Baráth; B Schuknecht; A Monge Naldi; T Schrepfer; C J Bockisch; S C A Hegemann Journal: AJNR Am J Neuroradiol Date: 2014-02-13 Impact factor: 3.825