Literature DB >> 21732071

The genotoxic effect of radiofrequency waves on mouse brain.

Emin Karaca1, Burak Durmaz, Huseyin Aktug, Huseyin Altug, Teoman Yildiz, Candan Guducu, Melis Irgi, Mehtap Gulcihan Cinar Koksal, Ferda Ozkinay, Cumhur Gunduz, Ozgur Cogulu.   

Abstract

Concerns about the health effects of radiofrequency (RF) waves have been raised because of the gradual increase in usage of cell phones, and there are scientific questions and debates about the safety of those instruments in daily life. The aim of this study is to evaluate the genotoxic effects of RF waves in an experimental brain cell culture model. Brain cell cultures of the mice were exposed to 10.715 GHz with specific absorbtion rate (SAR) 0.725 W/kG signals for 6 h in 3 days at 25°C to check for the changes in the micronucleus (MNi) assay and in the expression of 11 proapoptotic and antiapoptotic genes. It was found that MNi rate increased 11-fold and STAT3 expression decreased 7-fold in the cell cultures which were exposed to RF. Cell phones which spread RF may damage DNA and change gene expression in brain cells.

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Year:  2011        PMID: 21732071     DOI: 10.1007/s11060-011-0644-z

Source DB:  PubMed          Journal:  J Neurooncol        ISSN: 0167-594X            Impact factor:   4.130


  24 in total

1.  Non-thermal DNA breakage by mobile-phone radiation (1800 MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro.

Authors:  Elisabeth Diem; Claudia Schwarz; Franz Adlkofer; Oswald Jahn; Hugo Rüdiger
Journal:  Mutat Res       Date:  2005-06-06       Impact factor: 2.433

2.  Exposure to radiofrequency radiation (900 MHz, GSM signal) does not affect micronucleus frequency and cell proliferation in human peripheral blood lymphocytes: an interlaboratory study.

Authors:  Maria Rosaria Scarfì; Anna Maria Fresegna; Paola Villani; Rosanna Pinto; Carmela Marino; Maurizio Sarti; Pierluigi Altavista; Anna Sannino; Giorgio A Lovisolo
Journal:  Radiat Res       Date:  2006-06       Impact factor: 2.841

3.  Cytogenetic investigation of subjects professionally exposed to radiofrequency radiation.

Authors:  Annemarie Maes; Urbain Van Gorp; Luc Verschaeve
Journal:  Mutagenesis       Date:  2006-02-15       Impact factor: 3.000

4.  Combinative exposure effect of radio frequency signals from CDMA mobile phones and aphidicolin on DNA integrity.

Authors:  R Tiwari; N K Lakshmi; V Surender; A D V Rajesh; S C Bhargava; Y R Ahuja
Journal:  Electromagn Biol Med       Date:  2008       Impact factor: 2.882

Review 5.  An epidemiological review of mobile telephones and cancer.

Authors:  Sumedh S Hoskote; Mukta Kapdi; Shashank R Joshi
Journal:  J Assoc Physicians India       Date:  2008-12

6.  [An experimental in-vitro evaluation of membrane antigen expression and of interleukin production by monocytes exposed to magnetic resonance].

Authors:  R Lagalla; D Lio; F Gervasi; M De Maria; A Lo Casto; S Salerno; A E Cardinale
Journal:  Radiol Med       Date:  1996-03       Impact factor: 3.469

7.  Measurement of micronuclei in lymphocytes.

Authors:  M Fenech; A A Morley
Journal:  Mutat Res       Date:  1985 Feb-Apr       Impact factor: 2.433

8.  Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes.

Authors:  Tian-Yong Zhao; Shi-Ping Zou; Pamela E Knapp
Journal:  Neurosci Lett       Date:  2006-12-21       Impact factor: 3.046

9.  STAT3 signalling pathway is involved in the activation of microglia induced by 2.45 GHz electromagnetic fields.

Authors:  Yutong Hao; Xuesen Yang; Chunhai Chen; Xubu Wang; Maoquan Li; Zhengping Yu
Journal:  Int J Radiat Biol       Date:  2010-01       Impact factor: 2.694

10.  Mobile phone use, exposure to radiofrequency electromagnetic field, and brain tumour: a case-control study.

Authors:  T Takebayashi; N Varsier; Y Kikuchi; K Wake; M Taki; S Watanabe; S Akiba; N Yamaguchi
Journal:  Br J Cancer       Date:  2008-02-05       Impact factor: 7.640

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  8 in total

1.  Analysis of the Genotoxic Effects of Mobile Phone Radiation using Buccal Micronucleus Assay: A Comparative Evaluation.

Authors:  Sumita Banerjee; Narendra Nath Singh; Gadiputi Sreedhar; Saikat Mukherjee
Journal:  J Clin Diagn Res       Date:  2016-03-01

2.  Exposure to 1950-MHz TD-SCDMA electromagnetic fields affects the apoptosis of astrocytes via caspase-3-dependent pathway.

Authors:  Yu-xiao Liu; Jun-li Tai; Guo-qing Li; Zhi-wen Zhang; Jing-hui Xue; Hong-sheng Liu; Heng Zhu; Ji-de Cheng; Yuan-Ling Liu; An-ming Li; Yi Zhang
Journal:  PLoS One       Date:  2012-08-01       Impact factor: 3.240

3.  Neural cell apoptosis induced by microwave exposure through mitochondria-dependent caspase-3 pathway.

Authors:  Hongyan Zuo; Tao Lin; Dewen Wang; Ruiyun Peng; Shuiming Wang; Yabing Gao; Xinping Xu; Yang Li; Shaoxia Wang; Li Zhao; Lifeng Wang; Hongmei Zhou
Journal:  Int J Med Sci       Date:  2014-03-09       Impact factor: 3.738

4.  Effects of combined radiofrequency field exposure on amyloid-beta-induced cytotoxicity in HT22 mouse hippocampal neurones.

Authors:  Jong-Sun Lee; Jeong-Yub Kim; Hee-Jin Kim; Jeong Cheol Kim; Jae-Seon Lee; Nam Kim; Myung-Jin Park
Journal:  J Radiat Res       Date:  2016-06-20       Impact factor: 2.724

5.  Evaluation of bax, bcl-2, p21 and p53 genes expression variations on cerebellum of BALB/c mice before and after birth under mobile phone radiation exposure.

Authors:  Najmeh Ghatei; Ariane Sadr Nabavi; Mohammad Hossein Bahreyni Toosi; Hosein Azimian; Mansour Homayoun; Reza Ghasemnezhad Targhi; Hossein Haghir
Journal:  Iran J Basic Med Sci       Date:  2017-09       Impact factor: 2.699

Review 6.  Establishment of injury models in studies of biological effects induced by microwave radiation.

Authors:  Yun-Fei Lai; Hao-Yu Wang; Rui-Yun Peng
Journal:  Mil Med Res       Date:  2021-02-18

Review 7.  Radiofrequency Electromagnetic Field Exposure and Apoptosis: A Scoping Review of In Vitro Studies on Mammalian Cells.

Authors:  Stefania Romeo; Olga Zeni; Maria Rosaria Scarfì; Loredana Poeta; Maria Brigida Lioi; Anna Sannino
Journal:  Int J Mol Sci       Date:  2022-02-19       Impact factor: 5.923

Review 8.  Quality Matters: Systematic Analysis of Endpoints Related to "Cellular Life" in Vitro Data of Radiofrequency Electromagnetic Field Exposure.

Authors:  Myrtill Simkó; Daniel Remondini; Olga Zeni; Maria Rosaria Scarfi
Journal:  Int J Environ Res Public Health       Date:  2016-07-12       Impact factor: 3.390

  8 in total

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