Literature DB >> 21729236

Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium.

C S Tam1, H-R Berthoud, M Bueter, M V Chakravarthy, A Geliebter, A Hajnal, J Holst, L Kaplan, W Pories, H Raybould, R Seeley, A Strader, E Ravussin.   

Abstract

Bariatric surgery is the most effective method for promoting dramatic and durable weight loss in morbidly obese subjects. Furthermore, type 2 diabetes is resolved in over 80% of patients. The mechanisms behind the amelioration in metabolic abnormalities are largely unknown but may be due to changes in energy metabolism, gut peptides and food preference. The goal of this meeting was to review the latest research to better understand the mechanisms behind the 'magic' of bariatric surgery. Replication of these effects in a non-surgical manner remains one of the ultimate challenges for the treatment of obesity and diabetes. Promising data on energy metabolism, gastrointestinal physiology, hedonic response and food intake were reviewed and discussed.
© 2011 The Authors. obesity reviews © 2011 International Association for the Study of Obesity.

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Year:  2011        PMID: 21729236      PMCID: PMC4048708          DOI: 10.1111/j.1467-789X.2011.00902.x

Source DB:  PubMed          Journal:  Obes Rev        ISSN: 1467-7881            Impact factor:   9.213


  50 in total

Review 1.  The neurohormonal regulation of energy intake in relation to bariatric surgery for obesity.

Authors:  Christopher N Ochner; Charlisa Gibson; Susan Carnell; Carl Dambkowski; Allan Geliebter
Journal:  Physiol Behav       Date:  2010-05-08

2.  Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation.

Authors:  Claire Barbier de La Serre; Collin L Ellis; Jennifer Lee; Amber L Hartman; John C Rutledge; Helen E Raybould
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-05-27       Impact factor: 4.052

3.  Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities.

Authors:  Rohit Kohli; Michelle Kirby; Kenneth D R Setchell; Pinky Jha; Kori Klustaitis; Laura A Woollett; Paul T Pfluger; William F Balistreri; Patrick Tso; Ronald J Jandacek; Stephen C Woods; James E Heubi; Matthias H Tschoep; David A D'Alessio; Noah F Shroyer; Randy J Seeley
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-07-01       Impact factor: 4.052

4.  Ileal interposition surgery improves glucose and lipid metabolism and delays diabetes onset in the UCD-T2DM rat.

Authors:  Bethany P Cummings; April D Strader; Kimber L Stanhope; James L Graham; Jennifer Lee; Helen E Raybould; Denis G Baskin; Peter J Havel
Journal:  Gastroenterology       Date:  2010-03-10       Impact factor: 22.682

Review 5.  Insights into amylin-leptin synergy.

Authors:  James L Trevaskis; David G Parkes; Jonathan D Roth
Journal:  Trends Endocrinol Metab       Date:  2010-04-21       Impact factor: 12.015

6.  Medication utilization and annual health care costs in patients with type 2 diabetes mellitus before and after bariatric surgery.

Authors:  Martin A Makary; Jeanne M Clark; Jeanne M Clarke; Andrew D Shore; Thomas H Magnuson; Thomas Richards; Eric B Bass; Francesca Dominici; Jonathan P Weiner; Albert W Wu; Jodi B Segal
Journal:  Arch Surg       Date:  2010-08

7.  The importance of caloric restriction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery.

Authors:  James M Isbell; Robyn A Tamboli; Erik N Hansen; Jabbar Saliba; Julia P Dunn; Sharon E Phillips; Pamela A Marks-Shulman; Naji N Abumrad
Journal:  Diabetes Care       Date:  2010-04-05       Impact factor: 19.112

8.  Gastric bypass increases energy expenditure in rats.

Authors:  Marco Bueter; Christian Löwenstein; Torsten Olbers; Maggie Wang; Nina L Cluny; Stephen R Bloom; Keith A Sharkey; Thomas A Lutz; Carel W le Roux
Journal:  Gastroenterology       Date:  2009-11-18       Impact factor: 22.682

Review 9.  Relative changes in resting energy expenditure during weight loss: a systematic review.

Authors:  A Schwartz; E Doucet
Journal:  Obes Rev       Date:  2009-09-17       Impact factor: 9.213

10.  High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse.

Authors:  Shengli Ding; Michael M Chi; Brooks P Scull; Rachael Rigby; Nicole M J Schwerbrock; Scott Magness; Christian Jobin; Pauline K Lund
Journal:  PLoS One       Date:  2010-08-16       Impact factor: 3.240

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  21 in total

Review 1.  [Surgery as pluripotent instrument for metabolic disease. What are the mechanisms?].

Authors:  C Corteville; M Fassnacht; M Bueter
Journal:  Chirurg       Date:  2014-11       Impact factor: 0.955

Review 2.  Roux-en-Y gastric bypass: effects on feeding behavior and underlying mechanisms.

Authors:  Sean Manning; Andrea Pucci; Rachel L Batterham
Journal:  J Clin Invest       Date:  2015-03-02       Impact factor: 14.808

Review 3.  Proceedings of the 2017 ASPEN Research Workshop-Gastric Bypass: Role of the Gut.

Authors:  Ajay Kumar Jain; Carel W le Roux; Puneet Puri; Ali Tavakkoli; Nana Gletsu-Miller; Blandine Laferrère; Richard Kellermayer; John K DiBaise; Robert G Martindale; Bruce M Wolfe
Journal:  JPEN J Parenter Enteral Nutr       Date:  2018-02       Impact factor: 4.016

Review 4.  ApoA-IV: current and emerging roles in intestinal lipid metabolism, glucose homeostasis, and satiety.

Authors:  Alison B Kohan; Fei Wang; Chun-Min Lo; Min Liu; Patrick Tso
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2015-01-15       Impact factor: 4.052

5.  Roux-en-Y gastric bypass in mice--surgical technique and characterisation.

Authors:  F Seyfried; M Lannoo; W Gsell; J L Tremoleda; M Bueter; T Olbers; C Jurowich; C-T Germer; C W le Roux
Journal:  Obes Surg       Date:  2012-07       Impact factor: 4.129

6.  Roux-en-Y gastric bypass surgery increases number but not density of CCK-, GLP-1-, 5-HT-, and neurotensin-expressing enteroendocrine cells in rats.

Authors:  M B Mumphrey; L M Patterson; H Zheng; H-R Berthoud
Journal:  Neurogastroenterol Motil       Date:  2012-10-24       Impact factor: 3.598

7.  Laparoscopic Roux-en-Y gastric bypass in super obese Göttingen minipigs.

Authors:  Malene M Birck; Andreas Vegge; Mikael Støckel; Ismail Gögenur; Thomas Thymann; Karsten P Hammelev; Per T Sangild; Axel K Hansen; Kirsten Raun; Pia von Voss; Thomas Eriksen
Journal:  Am J Transl Res       Date:  2013-09-25       Impact factor: 4.060

Review 8.  Apolipoprotein A-IV: a protein intimately involved in metabolism.

Authors:  Fei Wang; Alison B Kohan; Chun-Min Lo; Min Liu; Philip Howles; Patrick Tso
Journal:  J Lipid Res       Date:  2015-02-01       Impact factor: 5.922

9.  Sugar Detection Threshold After Laparoscopic Sleeve Gastrectomy in Adolescents.

Authors:  Ghalia N Abdeen; Alexander D Miras; Aayed R Alqhatani; Carel W le Roux
Journal:  Obes Surg       Date:  2018-05       Impact factor: 4.129

10.  Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance.

Authors:  Keval Chandarana; Cigdem Gelegen; Elaine E Irvine; Agharul I Choudhury; Chloé Amouyal; Fabrizio Andreelli; Dominic J Withers; Rachel L Batterham
Journal:  Mol Metab       Date:  2013-03-14       Impact factor: 7.422

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